{"id":"W2604342111","doi":"10.1111/vox.12518","title":"Early γ‐irradiation and subsequent storage of red cells in <scp>SAG</scp>‐M additive solution potentiate energy imbalance, microvesiculation and susceptibility to stress‐induced apoptotic cell death","year":2017,"lang":"en","type":"article","venue":"Vox Sanguinis","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; McMaster University; Canadian Blood Services","funders":"Health Canada; Australian Government; Government of Canada; Burroughs Wellcome Fund","keywords":"Phosphatidylserine; Apoptosis; Irradiation; Programmed cell death; Red blood cell; Cytosol; Andrology; Oxidative stress; Chemistry; Biophysics; Biology; Immunology; Cell biology; Biochemistry; Membrane; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001090889,0.0002911226,0.0002490088,0.0001355881,0.00009759545,0.0002206057,0.000161609,0.000256681,0.001869261],"category_scores_gemma":[0.00009248717,0.00008725553,0.0001704783,0.0001218302,0.0001606872,0.0001556616,0.0001711568,0.0004030908,0.0002047375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001559581,"about_ca_system_score_gemma":0.0001164051,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003485863,"about_ca_topic_score_gemma":0.0004708502,"domain_scores_codex":[0.9999262,0.00001872245,0.000008303028,0.00001478691,0.00001616089,0.00001573119],"domain_scores_gemma":[0.9999489,0.00001207353,0.00001513803,0.000009458222,0.000007176323,0.000007293151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002904024,0.00002162289,0.0002162125,0.00004436111,0.00001075479,0.00006330676,0.00002736159,0.00006363958,0.9973831,0.00006339232,0.00003002651,0.001785985],"study_design_scores_gemma":[0.000007294878,0.0005767833,0.003034884,0.000008172043,0.00002277354,0.0002208566,0.00002530411,0.0002149064,0.9945282,0.00003603948,0.001321359,0.000003400233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937172,0.00264882,0.002428913,0.00005676778,0.00002562651,0.00002910307,0.0001310061,0.00004737262,0.0009152686],"genre_scores_gemma":[0.9961111,0.0008281718,0.00129741,0.00004613414,0.000008275626,0.00002141345,0.00022769,0.00001307593,0.001446741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001869261,"threshold_uncertainty_score":0.006253302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01611032145133122,"score_gpt":0.2466994833151337,"score_spread":0.2305891618638025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}