{"id":"W2604342111","doi":"10.1111/vox.12518","title":"Early γ‐irradiation and subsequent storage of red cells in <scp>SAG</scp>‐M additive solution potentiate energy imbalance, microvesiculation and susceptibility to stress‐induced apoptotic cell death","year":2017,"lang":"en","type":"article","venue":"Vox Sanguinis","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; McMaster University; Canadian Blood Services","funders":"Health Canada; Australian Government; Government of Canada; Burroughs Wellcome Fund","keywords":"Phosphatidylserine; Apoptosis; Irradiation; Programmed cell death; Red blood cell; Cytosol; Andrology; Oxidative stress; Chemistry; Biophysics; Biology; Immunology; Cell biology; Biochemistry; Membrane; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001701868,0.0001671929,0.0003392722,0.0001660884,0.0001246043,0.00002752414,0.00006066201,0.0001657966,0.00001636068],"category_scores_gemma":[0.0001760977,0.0001642441,0.00005366603,0.00008801572,0.00007399864,0.000132574,0.00005378101,0.0001216011,0.000005160994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007886316,"about_ca_system_score_gemma":0.00004874092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001150033,"about_ca_topic_score_gemma":0.0003284205,"domain_scores_codex":[0.9988084,0.0001088735,0.0003043365,0.0004001911,0.0001451164,0.0002330578],"domain_scores_gemma":[0.9989783,0.00009283853,0.0002821546,0.0003739602,0.0001292845,0.0001434307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001423709,0.0001422556,0.05176644,0.00008882225,0.00002108111,0.00001479091,0.0008035357,0.00002212625,0.9450048,0.0000447307,0.0003087503,0.0016403],"study_design_scores_gemma":[0.001377704,0.0005397658,0.8698786,0.00007960315,0.00004706098,0.000003969515,0.0001829012,0.0006818237,0.1269078,0.00006685329,0.0001647692,0.0000691405],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981357,0.0001237669,0.0002165432,0.0001022222,0.0002641529,0.0003396051,0.00009624464,0.00002185629,0.0006999443],"genre_scores_gemma":[0.9987949,0.0001354498,0.0003978463,0.0001085878,0.0001179989,0.00001580164,0.0001178878,0.00001675924,0.0002947466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8181122,"threshold_uncertainty_score":0.6697678,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01611032145133122,"score_gpt":0.2466994833151337,"score_spread":0.2305891618638025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}