{"id":"W2604376281","doi":"10.1371/journal.pone.0174682","title":"Unusually high mechanical stability of bacterial adhesin extender domains having calcium clamps","year":2017,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Force Microscopy Techniques and Applications","field":"Physics and Astronomy","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Ministerie van Onderwijs, Cultuur en Wetenschap; Canadian Institutes of Health Research; European Commission","keywords":"Force spectroscopy; Extender; Calcium; Atomic force microscopy; Bacterial adhesin; Biophysics; Hydrogen bond; Chemistry; Crystallography; Stability (learning theory); Molecule; Materials science; Topology (electrical circuits); Nanotechnology; Biochemistry; Computer science; Biology; Mathematics; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001501779,0.0001257675,0.0002677476,0.0000181394,0.0002633679,0.00007281775,0.0003623367,0.00006010569,0.001117305],"category_scores_gemma":[0.00001337196,0.0001226147,0.00008592709,0.00002908581,0.0001224572,0.0001153606,0.0001749253,0.0001415461,0.00001528943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002510204,"about_ca_system_score_gemma":0.00004870264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005016354,"about_ca_topic_score_gemma":0.00001376048,"domain_scores_codex":[0.9990863,0.0000254144,0.0002652081,0.00025546,0.0001568842,0.0002106937],"domain_scores_gemma":[0.9987769,0.00003023727,0.0002135042,0.000816687,0.00009135158,0.00007135265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002487135,0.001181987,0.004009465,0.0000237793,0.00007141612,1.846248e-7,0.00004819167,1.016931e-7,0.9200448,0.07400507,0.0000905634,0.0004995549],"study_design_scores_gemma":[0.000328477,0.00006704204,0.005671485,0.00005747605,0.00007686936,6.628251e-8,0.00004090381,0.00006546571,0.9830768,0.01028397,0.0001843899,0.0001470767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861361,0.000003189909,0.0104993,0.0002161883,0.00003144705,0.000324385,0.0001971869,0.00004578509,0.002546361],"genre_scores_gemma":[0.9817689,0.000001253453,0.01770208,0.00001132177,0.000222213,0.00007089326,0.00005546584,0.0000195183,0.0001483511],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0637211,"threshold_uncertainty_score":0.9997958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0596482621374607,"score_gpt":0.2930160948966251,"score_spread":0.2333678327591644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}