{"id":"W2604383404","doi":"10.1016/j.ctrv.2017.03.011","title":"Efficacy, safety, tolerability and price of newly approved drugs in solid tumors","year":2017,"lang":"en","type":"review","venue":"Cancer Treatment Reviews","topic":"Economic and Financial Impacts of Cancer","field":"Economics, Econometrics and Finance","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; Tolerability; Discontinuation; Internal medicine; Hazard ratio; Oncology; Chemotherapy; Immunotherapy; Adverse effect; Cancer; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001718393,0.0005237428,0.001662037,0.001502645,0.0001125154,0.0009113598,0.0005577224,0.0006708328,0.002934991],"category_scores_gemma":[0.00371881,0.0002297412,0.001405665,0.002523757,0.0003063748,0.0007045097,0.000316871,0.001077593,0.0002502082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008503355,"about_ca_system_score_gemma":0.001199026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002038636,"about_ca_topic_score_gemma":0.005278987,"domain_scores_codex":[0.999405,0.0001971564,0.00009954895,0.00006136239,0.0002063664,0.00003046652],"domain_scores_gemma":[0.9975801,0.001773058,0.0004411762,0.00002366064,0.0001501344,0.00003192394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0003917873,0.00007705462,0.0009567428,0.06842485,0.001939337,0.0001002227,0.00003352401,0.001570216,0.0004496916,0.003848293,0.01514054,0.9070678],"study_design_scores_gemma":[0.0005792267,0.001103206,0.02429989,0.0808616,0.01496895,0.002184142,0.0002312342,0.001819745,0.001241143,0.01336712,0.8592209,0.0001227495],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001931013,0.9994196,0.00003263884,0.0001155826,0.00002757416,0.000002168628,0.00001954876,9.64537e-7,0.0001889713],"genre_scores_gemma":[0.004053205,0.9955439,0.00009329987,0.0001058597,0.0000925033,0.000003872638,0.00002359188,6.572966e-7,0.00008305151],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002934991,"threshold_uncertainty_score":0.009818554,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1432827088296628,"score_gpt":0.3700561566682588,"score_spread":0.226773447838596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}