{"id":"W2604441277","doi":"10.1161/jaha.116.004965","title":"Intracellular Angiotensin‐II Interacts With Nuclear Angiotensin Receptors in Cardiac Fibroblasts and Regulates RNA Synthesis, Cell Proliferation, and Collagen Secretion","year":2017,"lang":"en","type":"article","venue":"Journal of the American Heart Association","topic":"Renin-Angiotensin System Studies","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Institut National de la Recherche Scientifique; Université de Montréal; Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Intracellular; Medicine; Angiotensin II; Secretion; Cell biology; Receptor; Renin–angiotensin system; Cell growth; RNA; Cell; Angiotensin receptor; Internal medicine; Endocrinology; Biochemistry; Biology; Gene; Blood pressure","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001232355,0.0001919308,0.000164831,0.0001456773,0.0001493111,0.0002260539,0.0001111399,0.0001640449,0.0007912166],"category_scores_gemma":[0.00008920716,0.0001100433,0.0002114615,0.00009040428,0.0001226473,0.0001138734,0.0000910872,0.0002107159,0.0003060636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000236223,"about_ca_system_score_gemma":0.0001128444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009781991,"about_ca_topic_score_gemma":0.001765469,"domain_scores_codex":[0.9998647,0.00002661868,0.00000755125,0.0000315672,0.0000404579,0.00002920191],"domain_scores_gemma":[0.9999325,0.00002208541,0.00001302534,0.000008390107,0.000008101186,0.0000158521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004067639,0.000005255547,0.0002535782,0.0000184446,0.000002387776,0.00005475465,0.00001103867,0.00001645211,0.9988855,0.0000454061,0.00002388894,0.0006426267],"study_design_scores_gemma":[0.00003799648,0.0003965998,0.04033496,0.00001377004,0.00003391167,0.000980251,0.0001075898,0.00139082,0.9524344,0.0001553186,0.0041006,0.00001362386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850272,0.005706894,0.0048046,0.0001169966,0.0000541899,0.00001982525,0.0003618151,0.00007591096,0.003832575],"genre_scores_gemma":[0.9939567,0.001402709,0.002376266,0.00007172567,0.00003044375,0.00003051677,0.000261812,0.00001258939,0.001857339],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009781991,"threshold_uncertainty_score":0.002646923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006828510073759264,"score_gpt":0.2283432676447964,"score_spread":0.2215147575710371,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}