{"id":"W2604441806","doi":"10.1200/jco.2012.30.15_suppl.7541","title":"A phase II multicenter study of aflibercept (AFL) in combination with cisplatin (C) and pemetrexed (P) in patients with previously untreated advanced/metastatic nonsquamous non-small cell lung cancer (NSCLC).","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; Internal medicine; Lung cancer; Phases of clinical research; Nausea; Adverse effect; Chemotherapy; Pemetrexed; Gastroenterology; Aflibercept; Oncology; Chemotherapy regimen; Surgery; Cisplatin; Bevacizumab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002225999,0.001827831,0.001961286,0.0005433019,0.0004985743,0.0009538712,0.001008764,0.001293077,0.003036318],"category_scores_gemma":[0.001218074,0.0008846254,0.001052954,0.0004656372,0.001238717,0.001087317,0.0004232865,0.002775982,0.0008625022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000851611,"about_ca_system_score_gemma":0.001687308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009840276,"about_ca_topic_score_gemma":0.002052542,"domain_scores_codex":[0.999374,0.0003629317,0.00002725702,0.0001019781,0.00004359051,0.00009021084],"domain_scores_gemma":[0.9991834,0.0001308348,0.0001571748,0.00005860125,0.00004522048,0.0004247352],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7778355,0.1091867,0.005990026,0.0008203065,0.001187065,0.000302573,0.0004576932,0.002198453,0.03460124,0.0002598689,0.003241792,0.06391874],"study_design_scores_gemma":[0.6223246,0.3675154,0.005823642,0.00001948626,0.0002620213,0.0001685831,0.00004924461,0.0007859566,0.00156299,0.00008427545,0.001382753,0.00002110969],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928001,0.001615204,0.0005369442,0.0004404374,0.0001541423,0.002853497,0.0005422528,0.00007744176,0.0009799103],"genre_scores_gemma":[0.9898204,0.001418445,0.001604379,0.0008005727,0.0002419957,0.003061884,0.001360939,0.00002676058,0.001664622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003036318,"threshold_uncertainty_score":0.01177233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03250744216774533,"score_gpt":0.4334842109793013,"score_spread":0.400976768811556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}