{"id":"W2604441863","doi":"10.1158/1557-3125.dnarepair16-ia06","title":"Abstract IA06: The Fanconi anemia-BRCA pathway and cancer","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Fanconi anemia; Cancer; DNA repair; Cancer research; Cisplatin; FANCD2; Cancer cell; Biology; DNA damage; Carboplatin; Chromosome instability; Synthetic lethality; Genome instability; DNA; Genetics; Gene; Chromosome; Chemotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003779062,0.0006525497,0.0003921055,0.0008397079,0.0004519136,0.001205195,0.0005954635,0.00118813,0.01816938],"category_scores_gemma":[0.0002988922,0.000109569,0.0002982395,0.0007227444,0.0003597764,0.0009927338,0.0006575289,0.001294776,0.005237738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007089363,"about_ca_system_score_gemma":0.0004544424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001028878,"about_ca_topic_score_gemma":0.0006920848,"domain_scores_codex":[0.9998764,0.00002547969,0.000009865769,0.0000381178,0.00002865136,0.00002147034],"domain_scores_gemma":[0.9998436,0.00002636125,0.00002181786,0.000004784943,0.0000517121,0.00005170234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002890376,0.0001077711,0.001960005,0.002078019,0.00004993973,0.0009661558,0.0001644605,0.000407197,0.01549781,0.02619427,0.7193991,0.2328862],"study_design_scores_gemma":[0.00002110685,0.0001207083,0.004306923,0.0006966463,0.0000425919,0.001965404,0.0001696217,0.0003345528,0.004709571,0.009790589,0.9778194,0.0000229344],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.01130943,0.7484777,0.004048912,0.07571831,0.08614382,0.0001094904,0.001236778,0.0003177891,0.07263775],"genre_scores_gemma":[0.08392141,0.4740072,0.003092022,0.02288317,0.05999987,0.0001389218,0.002949235,0.0001156859,0.3528923],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.01816938,"threshold_uncertainty_score":0.06078261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04489407521984517,"score_gpt":0.3793007481798722,"score_spread":0.3344066729600271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}