{"id":"W2604598757","doi":"10.1158/1557-3125.dnarepair16-ia24","title":"Abstract IA24: Targeting Chk1","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cancer research; Cancer; CHEK1; Medicine; Cell cycle; Cell cycle checkpoint; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001635266,0.0006528946,0.0003126641,0.0004405327,0.0002161505,0.0005837921,0.0005664161,0.0003996622,0.007767145],"category_scores_gemma":[0.0001044949,0.0001288609,0.0002215057,0.0002866487,0.0001858382,0.000207847,0.0003353393,0.0009657651,0.00259763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007559486,"about_ca_system_score_gemma":0.0003777054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008225576,"about_ca_topic_score_gemma":0.001092498,"domain_scores_codex":[0.9999011,0.000009906951,0.000005208284,0.00002640468,0.00002689188,0.0000304343],"domain_scores_gemma":[0.9999522,0.000002180318,0.000007801307,0.00000384587,0.000006653063,0.00002737225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001676788,0.0005125219,0.0005861163,0.0003731164,0.00007197802,0.0002871147,0.00002607803,0.00131871,0.9073876,0.001432216,0.01460646,0.07172126],"study_design_scores_gemma":[0.0008329679,0.004503761,0.004554802,0.0000763202,0.0001378952,0.001769913,0.00002515136,0.002792717,0.8396376,0.000513136,0.1451257,0.00002999661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7816051,0.1076459,0.0168946,0.005086583,0.002523397,0.001251888,0.006522357,0.002115421,0.07635488],"genre_scores_gemma":[0.9071499,0.02321218,0.006376876,0.0009917583,0.0003420962,0.0003620147,0.004733364,0.0001181435,0.05671373],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007767145,"threshold_uncertainty_score":0.02598369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04982320604103904,"score_gpt":0.400008689464264,"score_spread":0.350185483423225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}