{"id":"W2604598757","doi":"10.1158/1557-3125.dnarepair16-ia24","title":"Abstract IA24: Targeting Chk1","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cancer research; Cancer; CHEK1; Medicine; Cell cycle; Cell cycle checkpoint; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001065697,0.0001546112,0.000134599,0.0000688954,0.0006181609,0.0002858153,0.0009485878,0.0001752279,0.0002354437],"category_scores_gemma":[0.0004960221,0.0001560116,0.0001202081,0.00005946354,0.0002142483,0.00001032107,0.0006488131,0.0003265734,0.0000936364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005057811,"about_ca_system_score_gemma":0.0002247142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000484768,"about_ca_topic_score_gemma":0.00007482475,"domain_scores_codex":[0.9979311,0.00009492499,0.000167744,0.0005686041,0.0005820527,0.0006555718],"domain_scores_gemma":[0.9982221,0.000009027036,0.00008493588,0.001236101,0.0002769504,0.000170851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005000392,0.00003060953,0.0006267113,0.00002680592,0.00004732851,0.0000789775,0.00001809235,0.00002433907,0.9886602,0.0003433246,0.004610118,0.00548351],"study_design_scores_gemma":[0.0003428579,0.00008952301,0.002109883,0.00002792121,0.000004465879,0.000003346642,0.00003265309,0.00003180897,0.9392146,0.0004486437,0.05750873,0.0001855803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97958,0.002200802,0.0004767439,0.000848506,0.00025129,0.0003089445,0.00001742867,0.00002310682,0.01629311],"genre_scores_gemma":[0.9964316,0.0003120557,0.0006186239,0.0001347301,0.0003532463,0.0001443067,0.00003046454,0.0000566898,0.001918209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05289861,"threshold_uncertainty_score":0.6361969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04982320604103904,"score_gpt":0.400008689464264,"score_spread":0.350185483423225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}