{"id":"W2604655625","doi":"10.1158/1557-3125.dnarepair16-a40","title":"Abstract A40: Profile of DNA repair status in a recently established panel of patient-derived ovarian carcinoma xenografts","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"ERCC1; FANCD2; FANCA; Biology; Nucleotide excision repair; DNA repair; DNA mismatch repair; Cancer research; Fanconi anemia; MLH1; Base excision repair; DNA damage; Cisplatin; PARP1; Molecular biology; Gene; Genetics; DNA; Poly ADP ribose polymerase; Polymerase","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007973014,0.0002039633,0.0003323524,0.0002248132,0.000127735,0.00004835707,0.0006457772,0.0002373204,0.0001152641],"category_scores_gemma":[0.0006471658,0.0002101463,0.0001838068,0.0002204194,0.0003284222,0.00001761634,0.0005842375,0.0003002475,0.000003773084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009181496,"about_ca_system_score_gemma":0.0006976123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005338079,"about_ca_topic_score_gemma":0.0007012173,"domain_scores_codex":[0.9971387,0.0002530246,0.0004789667,0.0006412743,0.0007265813,0.0007614474],"domain_scores_gemma":[0.9973453,0.00001971418,0.0002902102,0.001609149,0.0005530517,0.0001825374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005165616,0.0002021337,0.01521311,0.0001960708,0.00007545429,0.00009017625,0.0002310043,0.00002643923,0.9790972,0.0000682648,0.0003492144,0.003934368],"study_design_scores_gemma":[0.001118686,0.0004880368,0.04959314,0.0001053153,0.000009674379,0.000002430134,0.0002126648,0.0000546654,0.9464957,0.00009679601,0.001635566,0.0001873059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955168,0.001073435,0.00003425353,0.00009000337,0.0001459901,0.0008027733,0.0001190355,0.00001359237,0.002204138],"genre_scores_gemma":[0.9982595,0.0002377225,0.0009831781,0.00002347869,0.00004435101,0.0002153787,0.00007749558,0.00005373558,0.000105105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03438003,"threshold_uncertainty_score":0.8569519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04261307033363666,"score_gpt":0.3337992034683699,"score_spread":0.2911861331347333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}