{"id":"W2604655625","doi":"10.1158/1557-3125.dnarepair16-a40","title":"Abstract A40: Profile of DNA repair status in a recently established panel of patient-derived ovarian carcinoma xenografts","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"ERCC1; FANCD2; FANCA; Biology; Nucleotide excision repair; DNA repair; DNA mismatch repair; Cancer research; Fanconi anemia; MLH1; Base excision repair; DNA damage; Cisplatin; PARP1; Molecular biology; Gene; Genetics; DNA; Poly ADP ribose polymerase; Polymerase","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001809698,0.0001873589,0.0001891279,0.000245184,0.0001402474,0.0002493999,0.0001043746,0.0002281727,0.001873852],"category_scores_gemma":[0.0002367206,0.00009819946,0.0001299027,0.0002122364,0.0001290764,0.0001073035,0.0001433345,0.0003708435,0.0003644309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001605063,"about_ca_system_score_gemma":0.00009865881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004386496,"about_ca_topic_score_gemma":0.0004477698,"domain_scores_codex":[0.9998679,0.00001911343,0.00001249612,0.00004101195,0.0000374538,0.00002194412],"domain_scores_gemma":[0.9998004,0.00006793375,0.00002708578,0.00002987903,0.00003404842,0.00004072945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006466909,0.0001000956,0.0103868,0.00003482577,0.00001963086,0.0002020391,0.00006264612,0.0001691331,0.9857199,0.00004347252,0.0001076418,0.002507232],"study_design_scores_gemma":[0.00006511279,0.004554352,0.1625302,0.000009919898,0.0001073627,0.004961537,0.0002116736,0.001748678,0.8184707,0.00009547067,0.007231317,0.00001373731],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975654,0.0003560582,0.0006610153,0.00001725209,0.000007688774,0.00002240464,0.0008011966,0.00002845963,0.0005405208],"genre_scores_gemma":[0.9933962,0.0002891555,0.001095921,0.00003234479,0.00000635838,0.00005184431,0.003776647,0.00002258103,0.001328957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001873852,"threshold_uncertainty_score":0.00626868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04261307033363666,"score_gpt":0.3337992034683699,"score_spread":0.2911861331347333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}