{"id":"W2604730946","doi":"10.1158/1557-3125.dnarepair16-ia19","title":"Abstract IA19: PARP trapping and Schlafen 11","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Olaparib; Poly ADP ribose polymerase; Cancer research; PARP1; Biology; Cancer cell; Cancer; Homologous recombination; Polymerase; PARP inhibitor; Genetics; DNA","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001135976,0.0004765014,0.0002224541,0.0003764794,0.0002434835,0.00048464,0.0003966357,0.0003411243,0.004886352],"category_scores_gemma":[0.0001163759,0.0001837255,0.0002270451,0.0002893247,0.0002717066,0.0002674594,0.0003011611,0.0005430391,0.001386844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006418313,"about_ca_system_score_gemma":0.0002802527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001067879,"about_ca_topic_score_gemma":0.001065875,"domain_scores_codex":[0.9998939,0.00001069805,0.000007082208,0.00002952423,0.00003248016,0.00002636786],"domain_scores_gemma":[0.9999317,0.00001049712,0.00002797724,0.000007394985,0.000007339012,0.00001495119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001547826,0.00003162147,0.0006872633,0.00005935695,0.000008499494,0.0001502433,0.00001467938,0.0001721004,0.9869311,0.0004277173,0.0007073206,0.01065525],"study_design_scores_gemma":[0.00001622655,0.0002555823,0.004315742,0.000008787239,0.00001490307,0.0006186411,0.00001633159,0.0004814799,0.983033,0.0001158112,0.01111739,0.00000617351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9356363,0.01778552,0.01396633,0.001469084,0.0002587094,0.0001597905,0.002316068,0.000662257,0.02774587],"genre_scores_gemma":[0.9655461,0.005502853,0.00402471,0.0002136455,0.00004349558,0.0000473352,0.002894088,0.00006829556,0.02165945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004886352,"threshold_uncertainty_score":0.01634651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1694244475770431,"score_gpt":0.4950988911316901,"score_spread":0.325674443554647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}