{"id":"W2604730946","doi":"10.1158/1557-3125.dnarepair16-ia19","title":"Abstract IA19: PARP trapping and Schlafen 11","year":2017,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Olaparib; Poly ADP ribose polymerase; Cancer research; PARP1; Biology; Cancer cell; Cancer; Homologous recombination; Polymerase; PARP inhibitor; Genetics; DNA","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008341966,0.0001351324,0.0002342296,0.0001773457,0.0005800007,0.000198316,0.0002611671,0.0001085644,0.0006207897],"category_scores_gemma":[0.0001723195,0.0001280282,0.00007276097,0.0001158931,0.0005040584,0.000137355,0.000120887,0.0005304191,0.00004767913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001926686,"about_ca_system_score_gemma":0.0003581452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001404917,"about_ca_topic_score_gemma":0.0001197614,"domain_scores_codex":[0.9979988,0.00006558004,0.000185551,0.000423724,0.0008007813,0.0005255612],"domain_scores_gemma":[0.9984895,0.00004643616,0.00006998039,0.0008539456,0.0002595032,0.0002806587],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004474626,0.0001073348,0.02381045,0.0003353952,0.0001788157,0.0008439469,0.0003863578,0.00001061799,0.9118933,0.001633909,0.008216565,0.05213584],"study_design_scores_gemma":[0.006116947,0.0002568525,0.2537744,0.001250789,0.00004266956,0.00008264915,0.0001979534,0.0001525238,0.5760408,0.002235059,0.1594247,0.0004247108],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9578343,0.004133824,0.000172224,0.01676023,0.0001357234,0.0005615098,0.00001643534,0.00004583611,0.02033991],"genre_scores_gemma":[0.9966984,0.001183754,0.0001913598,0.0005008394,0.0002540812,0.0002162385,0.000005142459,0.00004193344,0.0009082917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3358525,"threshold_uncertainty_score":0.6797212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1694244475770431,"score_gpt":0.4950988911316901,"score_spread":0.325674443554647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}