{"id":"W2604772094","doi":"10.1091/mbc.e17-01-0018","title":"An endosomal syntaxin and the AP-3 complex are required for formation and maturation of candidate lysosome-related secretory organelles (mucocysts) in<i>Tetrahymena thermophila</i>","year":2017,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Japan Society for the Promotion of Science; National Institutes of Health; University of Alberta; University of Dundee; University of Chicago","keywords":"Tetrahymena; Biology; Cell biology; Syntaxin; Endosome; Endocytic cycle; Organelle; Lysosome; Secretory Vesicle; Vacuole; Secretory pathway; Secretion; Exocytosis; Endocytosis; Golgi apparatus; Genetics; Cytoplasm; Biochemistry; Endoplasmic reticulum; Cell","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001015284,0.0003413816,0.0002443968,0.0001810868,0.0002170793,0.0004128573,0.000319722,0.0004313528,0.0006720712],"category_scores_gemma":[0.0002155503,0.0002935231,0.0003076486,0.0001235856,0.000285015,0.0003308869,0.0004856111,0.0005591161,0.0003882766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004649251,"about_ca_system_score_gemma":0.0002640185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00123166,"about_ca_topic_score_gemma":0.001820849,"domain_scores_codex":[0.9998411,0.00001775036,0.00002897707,0.00003073229,0.00005349543,0.00002790186],"domain_scores_gemma":[0.9997512,0.0000278764,0.0001095493,0.00002408814,0.00001789916,0.00006942695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004621263,0.000003253094,0.000355809,0.00001646997,0.000003399078,0.00006782834,0.00001462565,0.0000247763,0.9992092,0.00004191759,0.00001346102,0.0002029742],"study_design_scores_gemma":[0.00002519602,0.000124166,0.08662101,0.00001450825,0.00004213551,0.0008728713,0.0001419476,0.002525812,0.9072165,0.0001408735,0.002258661,0.00001629956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975847,0.00040792,0.001258273,0.00005328067,0.00001039187,0.000009620296,0.0003396244,0.00004312447,0.0002930741],"genre_scores_gemma":[0.9964283,0.0001871108,0.001149095,0.00004620089,0.000003463877,0.00002735736,0.001051714,0.00004356885,0.001063268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00123166,"threshold_uncertainty_score":0.003373325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00764723352455736,"score_gpt":0.2296898291031417,"score_spread":0.2220425955785843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}