{"id":"W2604818452","doi":"10.1093/neuonc/nox030","title":"Point/counterpoint: randomized versus single-arm phase II clinical trials for patients with newly diagnosed glioblastoma","year":2017,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Counterpoint; Glioblastoma; Medicine; Clinical trial; Randomized controlled trial; Internal medicine; Psychology; Cancer research","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002433917,0.0004103022,0.002950983,0.0001658714,0.0004947837,0.00008181711,0.0002808219,0.0003248473,0.0002035703],"category_scores_gemma":[0.02674518,0.0002711865,0.0008827604,0.00006764061,0.0005363178,0.0001641273,0.0001507465,0.0002973266,0.000044976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002170804,"about_ca_system_score_gemma":0.0002966289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002864225,"about_ca_topic_score_gemma":0.00009982366,"domain_scores_codex":[0.9958912,0.0009979872,0.001474822,0.0007486685,0.0003456398,0.0005417],"domain_scores_gemma":[0.9805616,0.01605951,0.001536455,0.0009841893,0.0004082693,0.000450035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8141676,0.03449484,0.003732793,0.00003265101,0.001098352,0.0008071785,0.0001785981,0.000001663722,0.001758454,0.0002100384,0.01106022,0.1324576],"study_design_scores_gemma":[0.828968,0.1085718,0.0007443717,0.00007498829,0.002139011,0.00002229655,0.00002842571,0.000178672,0.002602476,0.00007677212,0.05637691,0.0002162955],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812217,0.00008019369,0.0001216936,0.007055509,0.003676535,0.006044762,0.00009605452,0.00009049586,0.001613049],"genre_scores_gemma":[0.9948549,0.0001023581,0.001086324,0.001785659,0.0008273985,0.001158772,0.00008422616,0.00007470734,0.00002569506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1322413,"threshold_uncertainty_score":0.999974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.093080814177779,"score_gpt":0.4171990285893885,"score_spread":0.3241182144116095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}