{"id":"W2604818452","doi":"10.1093/neuonc/nox030","title":"Point/counterpoint: randomized versus single-arm phase II clinical trials for patients with newly diagnosed glioblastoma","year":2017,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Counterpoint; Glioblastoma; Medicine; Clinical trial; Randomized controlled trial; Internal medicine; Psychology; Cancer research","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.02582144,0.001351372,0.003638523,0.001363554,0.0005314706,0.002476663,0.001437816,0.004024663,0.005207065],"category_scores_gemma":[0.03934013,0.0004133114,0.003548103,0.0008309733,0.001716206,0.003581271,0.001296111,0.004894705,0.0005994213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009536662,"about_ca_system_score_gemma":0.001285474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001609718,"about_ca_topic_score_gemma":0.0003867268,"domain_scores_codex":[0.9752696,0.02091859,0.001385398,0.00118754,0.0008422009,0.0003966999],"domain_scores_gemma":[0.9805319,0.01404371,0.002844469,0.0008945016,0.000663615,0.001021895],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.7101474,0.005088332,0.001492809,0.005936913,0.00460105,0.0001772951,0.0002848289,0.003750104,0.00216642,0.009709168,0.002390398,0.2542553],"study_design_scores_gemma":[0.7596306,0.1950059,0.002036004,0.001806142,0.003280729,0.0002211297,0.0001930616,0.006290784,0.001266678,0.01949728,0.01065874,0.0001129825],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.6055871,0.1723758,0.06833348,0.03437813,0.03334808,0.06631996,0.001433759,0.0008341633,0.01738949],"genre_scores_gemma":[0.8955271,0.01974881,0.04016266,0.01081427,0.004510933,0.02660389,0.0004737513,0.00006824964,0.002090361],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.9741786,"threshold_uncertainty_score":0.1365585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.093080814177779,"score_gpt":0.4171990285893885,"score_spread":0.3241182144116095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}