{"id":"W2605270513","doi":"10.1038/leu.2017.111","title":"Benefit of continuous treatment for responders with newly diagnosed multiple myeloma in the randomized FIRST trial","year":2017,"lang":"en","type":"article","venue":"Leukemia","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Charles-Le Moyne; Alberta Cancer Foundation; University of Calgary","funders":"Celgene","keywords":"Medicine; Lenalidomide; Thalidomide; Internal medicine; Multiple myeloma; Melphalan; Randomized controlled trial; Dexamethasone; Gastroenterology; Prednisone; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002541876,0.001169349,0.0029167,0.0003361712,0.0003397734,0.001292425,0.0008639683,0.002292593,0.008086854],"category_scores_gemma":[0.004023808,0.0004959986,0.00232873,0.0002773947,0.0007802508,0.001306378,0.0004588396,0.003489703,0.0007737188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006961981,"about_ca_system_score_gemma":0.0008083131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003788387,"about_ca_topic_score_gemma":0.0007671999,"domain_scores_codex":[0.9988112,0.0007754842,0.00005819738,0.0001686205,0.00005724661,0.0001291946],"domain_scores_gemma":[0.9964058,0.001428121,0.0008948933,0.0003231789,0.0001324798,0.0008155925],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9797336,0.002256827,0.0005779336,0.0004709527,0.0007195859,0.00004014132,0.00003281665,0.0003369776,0.000780769,0.0001652472,0.001356372,0.01352867],"study_design_scores_gemma":[0.9597934,0.03629148,0.001504341,0.00007837071,0.000429944,0.00005233601,0.00001153796,0.0004612415,0.0001723992,0.0003376226,0.0008547319,0.00001248134],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.965871,0.01602124,0.001167009,0.003794551,0.001819287,0.004419931,0.002231363,0.0003650732,0.004310526],"genre_scores_gemma":[0.9807934,0.002644088,0.002132532,0.002880451,0.001513481,0.005434183,0.001894803,0.00003563829,0.002671469],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008086854,"threshold_uncertainty_score":0.02705324,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03900635522089815,"score_gpt":0.3199864532362354,"score_spread":0.2809800980153372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}