{"id":"W2605270513","doi":"10.1038/leu.2017.111","title":"Benefit of continuous treatment for responders with newly diagnosed multiple myeloma in the randomized FIRST trial","year":2017,"lang":"en","type":"article","venue":"Leukemia","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Charles-Le Moyne; Alberta Cancer Foundation; University of Calgary","funders":"Celgene","keywords":"Medicine; Lenalidomide; Thalidomide; Internal medicine; Multiple myeloma; Melphalan; Randomized controlled trial; Dexamethasone; Gastroenterology; Prednisone; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005461114,0.0002137392,0.0008560325,0.0001069848,0.0002494739,0.00005621527,0.0002491544,0.00009339827,0.00002482357],"category_scores_gemma":[0.001821286,0.0001075351,0.0002703309,0.00006277507,0.0002651725,0.00007568516,0.00002544178,0.0001024123,0.0000066505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003826306,"about_ca_system_score_gemma":0.0003219915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004336471,"about_ca_topic_score_gemma":0.005207913,"domain_scores_codex":[0.9985451,0.00009920321,0.0003535611,0.0002857323,0.0003438898,0.0003725591],"domain_scores_gemma":[0.996228,0.002501185,0.0002420811,0.0008237813,0.00009054288,0.0001143679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9606542,0.0004549177,0.02229174,0.00004816076,0.0004075407,0.0002977444,0.001074298,0.00002494032,0.00008077933,0.0001424158,0.0002035141,0.01431975],"study_design_scores_gemma":[0.9413606,0.00320315,0.05033451,0.0001394103,0.0002130068,0.00001295174,0.0002759314,0.001327719,0.001466752,0.00008454926,0.00147575,0.0001056599],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900355,0.0001285051,0.00007679013,0.001238716,0.00006960356,0.00704087,0.00004803651,0.00001707905,0.001344939],"genre_scores_gemma":[0.9953291,0.0001027564,0.001150214,0.00006372798,0.0001335604,0.001843737,0.00006253638,0.00002478417,0.001289613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02804277,"threshold_uncertainty_score":0.6555476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03900635522089815,"score_gpt":0.3199864532362354,"score_spread":0.2809800980153372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}