{"id":"W2605296607","doi":"","title":"Cyclin B-Cdk1 enhances a phosphatase activity towards Akt substrates to form the negative feedback pathway in threshold-setting for meiotic resumption","year":2016,"lang":"en","type":"article","venue":"The Molecular Biology Society of Japan","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carbon Engineering (Canada)","funders":"","keywords":"Cyclin-dependent kinase 1; Cell biology; Protein kinase B; Phosphatase; Meiosis; Protein phosphatase 2; Cyclin B1; Chemistry; Cyclin B; Cyclin; Biology; Phosphorylation; Cell cycle; Biochemistry; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007464754,0.0002206911,0.0002389205,0.00001904416,0.0001468964,0.00001394631,0.000453372,0.0002514479,0.000004671238],"category_scores_gemma":[0.0001445065,0.0001205199,0.0003030472,0.0001142019,0.000383299,0.000007757136,0.0001793078,0.0001184349,0.000003385695],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000346384,"about_ca_system_score_gemma":0.00009933139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001087597,"about_ca_topic_score_gemma":0.0002365144,"domain_scores_codex":[0.9986929,0.0001245345,0.0002834327,0.0004175807,0.00008256382,0.0003989929],"domain_scores_gemma":[0.9990804,0.0001129793,0.0001913656,0.0004732482,0.00009164639,0.00005031301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000195045,0.00005796457,0.0007136267,0.00002078349,0.0001154723,1.227495e-7,0.0005797942,0.00001702541,0.9863811,0.0005017537,0.0003192921,0.01109802],"study_design_scores_gemma":[0.0007897937,0.0003605268,0.002085336,0.00004247301,0.00002319735,0.000002482746,0.0005031456,0.00008007305,0.992743,0.002298294,0.0008870116,0.0001846878],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820278,0.0006986611,0.01260967,0.003553165,0.00008538843,0.0008016927,0.0001691388,0.00000922109,0.0000452482],"genre_scores_gemma":[0.9969153,0.000271685,0.001512874,0.0009127635,0.00008377489,0.0001364899,0.00006805437,0.00002217497,0.00007693007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01488744,"threshold_uncertainty_score":0.491466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01226173109172927,"score_gpt":0.2782518013031816,"score_spread":0.2659900702114523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}