{"id":"W2605398561","doi":"","title":"St Johns wort reduces oral bioavailability of talinolol in healthy volunteers","year":2002,"lang":"en","type":"article","venue":"Clinical Pharmacology & Therapeutics","topic":"Natural Products and Biological Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Bioavailability; Medicine; Pharmacology; Traditional medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001531777,0.0001815315,0.0007052835,0.0001266091,0.00004830206,0.000004750584,0.0002696879,0.0004100418,0.002275794],"category_scores_gemma":[0.0002732893,0.000120169,0.0001990356,0.0005265242,0.001424915,0.00004099377,0.0001127701,0.001358176,0.00008308166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008040288,"about_ca_system_score_gemma":0.0001129876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002973003,"about_ca_topic_score_gemma":0.00001230488,"domain_scores_codex":[0.9972501,0.0004376483,0.0009962666,0.0005373326,0.0002503395,0.0005282939],"domain_scores_gemma":[0.9983245,0.0007745747,0.0001431339,0.0002801341,0.0002380744,0.0002396548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01563025,0.01462869,0.4710323,0.0002909878,0.001270022,0.0002021507,0.0002610527,0.000009013274,0.111029,0.00005532387,0.06610305,0.3194882],"study_design_scores_gemma":[0.02674039,0.03189936,0.4051651,0.0001508794,0.001296093,0.00006869385,0.0003166706,0.008118466,0.03687691,0.0008875371,0.4873955,0.001084422],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9507954,0.002953208,0.000002254448,0.04427812,0.0008337146,0.000662461,0.00001808405,0.00004198913,0.0004147403],"genre_scores_gemma":[0.9623208,0.009369954,0.0002955886,0.02715395,0.0003906227,0.00001074168,0.00001083254,0.00001362113,0.0004338677],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4212925,"threshold_uncertainty_score":0.9986362,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2927404578473435,"score_gpt":0.4987353434568204,"score_spread":0.2059948856094769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}