{"id":"W2605512187","doi":"10.1016/j.ccell.2017.03.009","title":"A CD276 Antibody Guided Missile with One Warhead and Two Targets: The Tumor and Its Vasculature","year":2017,"lang":"en","type":"letter","venue":"Cancer Cell","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Warhead; Antibody; Missile; Cancer research; Cell biology; Biology; Immunology; Aerospace engineering; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001732105,0.0004284982,0.0007072785,0.00005719089,0.0003845339,0.0001191695,0.0002974722,0.0002820078,0.0006127203],"category_scores_gemma":[0.00002836585,0.0002351713,0.0001134685,0.00006202449,0.000387264,0.0001086218,0.0001778009,0.001731252,0.00002390844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000669264,"about_ca_system_score_gemma":0.0003420409,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001928466,"about_ca_topic_score_gemma":0.0001223732,"domain_scores_codex":[0.99783,0.00007009989,0.0002272585,0.0006321192,0.0006452993,0.000595227],"domain_scores_gemma":[0.9986554,0.0001094993,0.0001783121,0.0006049572,0.0002326346,0.0002192313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003142716,0.000043888,0.001762207,0.00271845,0.0004269535,0.001823753,0.0002772028,6.989611e-7,0.004641432,0.0000154706,0.9869864,0.0009892858],"study_design_scores_gemma":[0.001674178,0.0002317252,0.003295598,0.0009748294,0.0003740757,0.0003964386,0.00001774577,0.0001029011,0.002042386,0.0000431932,0.9904888,0.0003581548],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.07196219,0.2149784,0.00000536683,0.6866831,0.0003594749,0.001623532,0.0004255723,0.00005273764,0.02390957],"genre_scores_gemma":[0.04460935,0.04132391,0.0005849669,0.5905331,0.01850579,0.000331066,0.001086787,0.0003270796,0.302698],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.2787884,"threshold_uncertainty_score":0.9590008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04231791717463927,"score_gpt":0.3476686511610076,"score_spread":0.3053507339863684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}