{"id":"W2605515582","doi":"10.1016/j.urology.2017.04.016","title":"Could Reduced Fluid Intake Cause the Placebo Effect Seen in Overactive Bladder Clinical Trials? Analysis of a Large Solifenacin Integrated Database","year":2017,"lang":"en","type":"article","venue":"Urology","topic":"Urinary Bladder and Prostate Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre; Health Sciences Centre","funders":"Allergan; Astellas Pharma; Ipsen; Pfizer","keywords":"Solifenacin; Medicine; Placebo; Overactive bladder; Urination; Urology; Randomized controlled trial; Urine; Fluid intake; Urinary bladder; Anesthesia; Urinary system; Internal medicine; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.02122079,0.0005625284,0.003042784,0.002529554,0.0004602717,0.002781492,0.001614146,0.0008277139,0.003049074],"category_scores_gemma":[0.08121645,0.0005226284,0.003298516,0.005142814,0.0006083872,0.001299437,0.001427741,0.0009117441,0.0003945724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001000534,"about_ca_system_score_gemma":0.003137331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003108413,"about_ca_topic_score_gemma":0.007092166,"domain_scores_codex":[0.9687926,0.01594852,0.007292437,0.003350667,0.003903315,0.0007124867],"domain_scores_gemma":[0.9030914,0.0565472,0.02851671,0.006330826,0.004291895,0.001222071],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.06043156,0.00052196,0.6717195,0.01944927,0.09769057,0.0004991406,0.0005973356,0.001440846,0.002443845,0.001976301,0.01477669,0.1284529],"study_design_scores_gemma":[0.01535052,0.003439118,0.8350199,0.003746476,0.09646849,0.0009185622,0.000534153,0.002826136,0.002760783,0.002111853,0.03666526,0.0001587151],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7936327,0.08935802,0.00578597,0.005350944,0.0003482206,0.001483356,0.09883089,0.0001935179,0.005016354],"genre_scores_gemma":[0.9383665,0.007372686,0.005109415,0.002493849,0.0002785457,0.00112224,0.04451467,0.0000844336,0.0006576275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9787792,"threshold_uncertainty_score":0.1122276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.148024780628517,"score_gpt":0.5066302745442658,"score_spread":0.3586054939157488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}