{"id":"W2605550306","doi":"10.1016/j.cpet.2017.02.005","title":"Multimodal PET Imaging of Amyloid and Tau Pathology in Alzheimer Disease and Non–Alzheimer Disease Dementias","year":2017,"lang":"en","type":"review","venue":"PET Clinics","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Institute on Deafness and Other Communication Disorders","keywords":"Medicine; Dementia; Neurodegeneration; Disease; Biomarker; Dementia with Lewy bodies; Amyloid (mycology); Pathology; Pet imaging; Tau pathology; Alzheimer's disease; Neuroscience; Neuroimaging; Molecular imaging; Positron emission tomography; Psychology; Psychiatry; Radiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006400091,0.000740309,0.002494504,0.000428582,0.0001727676,0.00006924875,0.0003054758,0.0001254214,0.0001032359],"category_scores_gemma":[0.0005754773,0.0006020656,0.000589608,0.0001387974,0.0007868962,0.0001965272,0.0005489862,0.0006540197,0.00005993715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004333778,"about_ca_system_score_gemma":0.001380477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007018033,"about_ca_topic_score_gemma":0.00001589138,"domain_scores_codex":[0.9960549,0.0003382615,0.001195636,0.001130836,0.0005243368,0.0007560611],"domain_scores_gemma":[0.9956745,0.0004552649,0.0007255856,0.001293071,0.0001698278,0.001681749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0008518116,0.001691882,0.1648951,0.007259313,0.01263557,0.02299233,0.00005353321,3.028695e-7,8.038338e-8,0.00002606327,0.000285577,0.7893084],"study_design_scores_gemma":[0.02457208,0.0009408634,0.4680644,0.0394524,0.2577771,0.001312534,0.000121131,0.002209549,0.000001196855,0.0009291052,0.2013231,0.003296577],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004442386,0.9917425,0.000002712918,0.0001631372,0.0001696699,0.002213663,0.001088996,0.00003026783,0.000146672],"genre_scores_gemma":[0.05422389,0.9437198,0.0003449091,0.0000906421,0.0001904564,0.0002886752,0.0009951437,0.0001203824,0.00002607639],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7860118,"threshold_uncertainty_score":0.9996431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09808500394814798,"score_gpt":0.4347883830703768,"score_spread":0.3367033791222288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}