{"id":"W2605601673","doi":"10.1200/jco.2016.70.3439","title":"Traceback: A Proposed Framework to Increase Identification and Genetic Counseling of <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers Through Family-Based Outreach","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre","funders":"","keywords":"Medicine; Genetic testing; Population; Genetic counseling; Outreach; Ovarian cancer; Family medicine; Cancer; Oncology; Gynecology; Internal medicine; Genetics; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03717701,0.002039353,0.000849709,0.004302443,0.007704085,0.01054748,0.00829272,0.008791978,0.0134589],"category_scores_gemma":[0.02248183,0.001088086,0.002708466,0.00217967,0.01428175,0.01024318,0.01265033,0.007389333,0.002039092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01297943,"about_ca_system_score_gemma":0.05369294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02024153,"about_ca_topic_score_gemma":0.02586412,"domain_scores_codex":[0.9728653,0.01864474,0.0006358747,0.003040717,0.00226413,0.002549167],"domain_scores_gemma":[0.9795516,0.009182257,0.001046295,0.000836308,0.00279423,0.006589358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0002698371,0.00208038,0.008798265,0.001268459,0.0001722395,0.0007701149,0.01152946,0.007426273,0.000900547,0.8048719,0.03852302,0.1233895],"study_design_scores_gemma":[0.001001338,0.002055903,0.005467755,0.002715919,0.0003623934,0.000961187,0.01973751,0.03688785,0.001567515,0.6960244,0.2328916,0.0003266127],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.01755994,0.003984649,0.4563733,0.3926824,0.001912395,0.004965411,0.0003736973,0.001396344,0.1207519],"genre_scores_gemma":[0.2803628,0.003266462,0.658847,0.0323179,0.0005431686,0.00647686,0.0004012158,0.000185434,0.0175992],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.03717701,"threshold_uncertainty_score":0.1966132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0529580053879871,"score_gpt":0.4202579191050163,"score_spread":0.3672999137170291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}