{"id":"W2605607300","doi":"10.71781/4896","title":"Engineering polymeric micelles for solubilization of poorly-water soluble drugs : a novel approach for oral drug delivery","year":2005,"lang":"en","type":"dissertation","venue":"Open MIND","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Solubilization; Micelle; Drug delivery; Drug; Water soluble; Chemistry; Nanotechnology; Pharmacology; Materials science; Medicine; Organic chemistry; Aqueous solution; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002865676,0.0004241962,0.0003562676,0.0003306094,0.0002644324,0.0007025697,0.0002699042,0.0004001303,0.002726301],"category_scores_gemma":[0.0002025218,0.0002098213,0.0003239083,0.0002426434,0.0002312014,0.0005201683,0.000292318,0.0005446777,0.001091125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005919086,"about_ca_system_score_gemma":0.0007809529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003716825,"about_ca_topic_score_gemma":0.008611741,"domain_scores_codex":[0.9998934,0.00001119872,0.000006634944,0.00001924956,0.00004661937,0.00002277412],"domain_scores_gemma":[0.999945,0.000008781292,0.00001126311,0.000003509606,0.0000213537,0.00001007297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003663503,0.00005526657,0.00003267402,0.0002127864,0.000008116577,0.00007940033,0.00004627649,0.0001737163,0.9662998,0.00139937,0.0009032519,0.03075277],"study_design_scores_gemma":[0.00005263313,0.0002807088,0.0004852559,0.00003935935,0.00004191604,0.0002043196,0.0000215683,0.0008826362,0.9391063,0.0002909824,0.05857709,0.00001717782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5193688,0.1851426,0.2219235,0.006753637,0.002140144,0.001564893,0.0008976194,0.001586301,0.06062252],"genre_scores_gemma":[0.5978045,0.1412889,0.1063262,0.001145432,0.0003424555,0.0004534809,0.0006831742,0.0003438988,0.151612],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003716825,"threshold_uncertainty_score":0.009120345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1069528095379781,"score_gpt":0.3994448568909008,"score_spread":0.2924920473529227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}