{"id":"W2605735165","doi":"10.1182/blood-2017-02-764662","title":"Multiple myeloma cells sent “PAKing”!","year":2017,"lang":"en","type":"letter","venue":"Blood","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Multiple myeloma; Kinase; Cancer research; Allosteric regulation; Medicine; Biology; Immunology; Internal medicine; Cell biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001038968,0.0007253423,0.0007298586,0.0004689935,0.002180049,0.002315504,0.0007657355,0.01153545,0.006803809],"category_scores_gemma":[0.006607667,0.0003264056,0.0008203576,0.0003663347,0.001465203,0.002336703,0.0008442328,0.02089473,0.006752725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001917084,"about_ca_system_score_gemma":0.001060738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001414043,"about_ca_topic_score_gemma":0.00220864,"domain_scores_codex":[0.9991745,0.0002463917,0.00007040684,0.00009159884,0.0002934142,0.0001236318],"domain_scores_gemma":[0.9986104,0.0006105162,0.0001330568,0.00007137031,0.0003196452,0.0002550357],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008525455,0.00003903669,0.0005945226,0.00004763439,0.00001895582,0.004144412,0.00007397535,0.00004491023,0.0003668988,0.002067589,0.9757701,0.01674674],"study_design_scores_gemma":[0.0001897921,0.0001485039,0.001033511,0.0001894951,0.00003934321,0.008247395,0.0003185344,0.0004201543,0.0007175914,0.008462916,0.9801856,0.00004713434],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.0007651836,0.003406094,0.0002193686,0.9510269,0.04056926,0.00002269142,0.00005559625,0.00009925148,0.003835669],"genre_scores_gemma":[0.007661412,0.003526447,0.0003771872,0.8899825,0.08403491,0.0000329106,0.00006397013,0.00004834147,0.01427236],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.01153545,"threshold_uncertainty_score":0.02276099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01721884095017334,"score_gpt":0.2445329053757748,"score_spread":0.2273140644256014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}