{"id":"W2605736219","doi":"10.1002/hep.29209","title":"H19 promotes cholestatic liver fibrosis by preventing ZEB1‐mediated inhibition of epithelial cell adhesion molecule","year":2017,"lang":"en","type":"article","venue":"Hepatology","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Yale Liver Center; National Institute of Environmental Health Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Cancer Institute; National Institute on Alcohol Abuse and Alcoholism; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China; Yale University; National Institutes of Health; Canadian Institutes of Health Research; Canadian Liver Foundation; U.S. Department of Veterans Affairs","keywords":"Epithelial cell adhesion molecule; Primary biliary cirrhosis; Biology; Gene knockdown; Cholestasis; Fibrosis; Internal medicine; Endocrinology; Hepatic stellate cell; Cell adhesion molecule; Cancer research; Immunology; Medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002024094,0.0001850729,0.0002466418,0.00006995065,0.0001940521,0.00003139463,0.0002900876,0.000347076,0.00007050192],"category_scores_gemma":[0.0003340725,0.0001943105,0.0001204132,0.00005604266,0.0001905521,0.000009869101,0.0003032653,0.0001797648,0.00003747997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002544738,"about_ca_system_score_gemma":0.0001071473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002192413,"about_ca_topic_score_gemma":0.0000586961,"domain_scores_codex":[0.9984748,0.000176158,0.0003016142,0.000457085,0.0002057192,0.0003846373],"domain_scores_gemma":[0.9987849,0.00002295593,0.0003183855,0.0006267229,0.0001469419,0.00010008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001092713,0.0001283239,0.0004941476,0.0001122119,0.00003066217,0.00001988392,0.00004020751,0.000002277855,0.9967737,0.00001736263,0.00122476,0.001047237],"study_design_scores_gemma":[0.001016542,0.0005149742,0.0002217923,0.00004944349,0.00002893906,0.0000181653,0.00001404026,0.0009784286,0.9948725,0.00006985004,0.002029506,0.0001857831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938341,0.0007980313,0.003976322,0.0001504495,0.0001130883,0.0004030219,0.0001108711,0.00001573562,0.0005983396],"genre_scores_gemma":[0.9979194,0.0004423529,0.0006712948,0.00007737202,0.00005344348,0.00004907572,0.0003369763,0.00004109937,0.0004089743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00408527,"threshold_uncertainty_score":0.7923751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01122076654353861,"score_gpt":0.2607895681368808,"score_spread":0.2495688015933421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}