{"id":"W2605736219","doi":"10.1002/hep.29209","title":"H19 promotes cholestatic liver fibrosis by preventing ZEB1‐mediated inhibition of epithelial cell adhesion molecule","year":2017,"lang":"en","type":"article","venue":"Hepatology","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Yale Liver Center; National Institute of Environmental Health Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Cancer Institute; National Institute on Alcohol Abuse and Alcoholism; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China; Yale University; National Institutes of Health; Canadian Institutes of Health Research; Canadian Liver Foundation; U.S. Department of Veterans Affairs","keywords":"Epithelial cell adhesion molecule; Primary biliary cirrhosis; Biology; Gene knockdown; Cholestasis; Fibrosis; Internal medicine; Endocrinology; Hepatic stellate cell; Cell adhesion molecule; Cancer research; Immunology; Medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001511147,0.0003424679,0.0002615227,0.0002925305,0.0001804098,0.0002409836,0.0001930756,0.0002165366,0.001904232],"category_scores_gemma":[0.00008415438,0.0002025317,0.0002527748,0.0001034395,0.0002988481,0.0001645599,0.0002025894,0.0006964931,0.0004965849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002342106,"about_ca_system_score_gemma":0.0001887192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007021484,"about_ca_topic_score_gemma":0.001167608,"domain_scores_codex":[0.9998631,0.000024307,0.00001407479,0.00002327105,0.00003013394,0.00004504522],"domain_scores_gemma":[0.9998827,0.00001799137,0.00003508914,0.00001163006,0.000008884903,0.00004371405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001781297,0.00005430853,0.0001359066,0.00002457943,0.000005039359,0.00001973284,0.00000610728,0.00002888992,0.9985344,0.00007084079,0.00004355335,0.0008985583],"study_design_scores_gemma":[0.00004800717,0.0005767322,0.002443605,0.000003012623,0.00001064762,0.00006464354,0.00001369178,0.0004168077,0.9946854,0.00003024813,0.00170387,0.000003230525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930832,0.001606507,0.002721656,0.0002002495,0.000048253,0.00005512337,0.0003927015,0.0001852237,0.001707006],"genre_scores_gemma":[0.9918141,0.001197295,0.002414385,0.00009817128,0.00002343136,0.00005472325,0.0005756924,0.00003732677,0.003784876],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001904232,"threshold_uncertainty_score":0.006370246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01122076654353861,"score_gpt":0.2607895681368808,"score_spread":0.2495688015933421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}