{"id":"W2605824322","doi":"10.1016/j.jgeb.2017.04.003","title":"Effect of adenovirus infection on transgene expression under the adenoviral MLP/TPL and the CMVie promoter/enhancer in CHO cells","year":2017,"lang":"en","type":"article","venue":"Journal of Genetic Engineering and Biotechnology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"","keywords":"Transgene; Enhancer; Biology; Over expression; Molecular biology; Cell biology; Adenoviridae; Genetic enhancement; Virology; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009544042,0.0005413146,0.0005275654,0.0003797632,0.0001891831,0.0006877921,0.0002869255,0.0003972299,0.001423834],"category_scores_gemma":[0.0003586465,0.0002700331,0.000429061,0.0003532146,0.0004182766,0.0003495419,0.0004619113,0.001097436,0.000487278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004479877,"about_ca_system_score_gemma":0.0004840216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001399949,"about_ca_topic_score_gemma":0.001629297,"domain_scores_codex":[0.9990857,0.0002249941,0.00015371,0.0001692656,0.0002058424,0.0001605559],"domain_scores_gemma":[0.9994884,0.0002336208,0.00005616275,0.00006617898,0.000057964,0.00009782409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001310382,0.00006144033,0.0001583332,0.0000508727,0.000008309225,0.00003158186,0.00003293541,0.00002680801,0.9986075,0.00008384668,0.00002171041,0.0007856816],"study_design_scores_gemma":[0.00001955284,0.0005901498,0.001841751,0.000009726645,0.00002554663,0.00008045272,0.00003646231,0.0003980667,0.9950184,0.00002277605,0.001950679,0.000006407894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884334,0.00334548,0.004290048,0.00008928285,0.0001216847,0.0001155648,0.0006559287,0.0001341527,0.002814455],"genre_scores_gemma":[0.9781332,0.002629751,0.01100863,0.0001197243,0.00003439712,0.000167826,0.001707156,0.00008925354,0.006110114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001423834,"threshold_uncertainty_score":0.005047441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006253077680963122,"score_gpt":0.2628849647708327,"score_spread":0.2566318870898696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}