{"id":"W2605852828","doi":"10.1093/cvr/cvx076","title":"Role of phosphatase and tensin homolog in hypoxic pulmonary vasoconstriction","year":2017,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; Canada Research Chairs; University Health Network; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; University of California, San Francisco","keywords":"Hypoxic pulmonary vasoconstriction; PTEN; Tensin; TRPC6; Phosphatase; Caveolae; Hypoxia (environmental); Biology; Vasoconstriction; Cell biology; TRPC; Internal medicine; Endocrinology; PI3K/AKT/mTOR pathway; Chemistry; Transient receptor potential channel; Signal transduction; Receptor; Medicine; Phosphorylation; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001609101,0.0002840574,0.000177144,0.0001721111,0.000189716,0.00027804,0.0001788159,0.0002567155,0.0009672559],"category_scores_gemma":[0.0001572276,0.0001015952,0.0001869857,0.000105251,0.0003426243,0.000256834,0.0002265056,0.0003371466,0.0001946729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001798947,"about_ca_system_score_gemma":0.0001734312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001254969,"about_ca_topic_score_gemma":0.0001256001,"domain_scores_codex":[0.9999244,0.00001212158,0.000005983209,0.00002204462,0.00001571851,0.00001965714],"domain_scores_gemma":[0.999918,0.00000968946,0.00003502892,0.000004974851,0.000006137471,0.00002620766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007309107,0.00008239847,0.003155329,0.0003155447,0.00003270952,0.001343286,0.0000519116,0.0004479113,0.9843974,0.001581311,0.0003901022,0.007471151],"study_design_scores_gemma":[0.0002744456,0.001856205,0.1148411,0.00005160458,0.0002505184,0.009523343,0.0002624053,0.00992382,0.8398377,0.003286318,0.01985666,0.00003596998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9754343,0.01367429,0.005476503,0.0008869423,0.00008511929,0.00005530668,0.0002854378,0.0001952932,0.003906765],"genre_scores_gemma":[0.9946029,0.003186478,0.0006304784,0.00008278331,0.00004135995,0.00002872515,0.0001682614,0.000005800124,0.001253149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009672559,"threshold_uncertainty_score":0.003235817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08611261009039338,"score_gpt":0.3355789866684363,"score_spread":0.2494663765780429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}