{"id":"W2606158726","doi":"10.1210/en.2016-1831","title":"Absence of Endothelial ERα Results in Arterial Remodeling and Decreased Stiffness in Western Diet–Fed Male Mice","year":2017,"lang":"en","type":"article","venue":"Endocrinology","topic":"Cardiovascular Health and Disease Prevention","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Université de Strasbourg; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of Missouri; U.S. Department of Veterans Affairs","keywords":"Endocrinology; Internal medicine; Elastin; Arterial stiffness; Estrogen receptor; Endothelial dysfunction; Endothelium; Mesenteric arteries; Vascular remodelling in the embryo; Receptor; Estrogen; Pulse wave velocity; Vasodilation; Medicine; Chemistry; Biology; Artery; Blood pressure; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004043592,0.0008562233,0.0005198712,0.001355548,0.0003296234,0.0005183156,0.000433634,0.0007280369,0.002876706],"category_scores_gemma":[0.0002607544,0.0008062987,0.000691678,0.0004553695,0.0005303629,0.0004648272,0.0003768871,0.001423844,0.0008568109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003081538,"about_ca_system_score_gemma":0.0002278833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005378738,"about_ca_topic_score_gemma":0.0008389126,"domain_scores_codex":[0.9993992,0.00008258518,0.0000857987,0.0002121126,0.0001303661,0.00009003504],"domain_scores_gemma":[0.9990452,0.00006705135,0.0004550456,0.0001140575,0.00005467156,0.0002639601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007218474,0.0002216323,0.0008716455,0.00004848247,0.00002916775,0.0001915397,0.00003782323,0.00005779484,0.9957051,0.0001746235,0.00009115456,0.001849228],"study_design_scores_gemma":[0.0003936599,0.003605798,0.0831027,0.00007882162,0.0002882661,0.00333924,0.0003075181,0.001871428,0.9004126,0.0004416454,0.006103149,0.00005523388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920843,0.0008486785,0.003967292,0.0002810081,0.00007322749,0.00003235004,0.001269795,0.0002596152,0.00118378],"genre_scores_gemma":[0.9763763,0.002070983,0.007463204,0.0004472306,0.00007497802,0.0001952029,0.001932614,0.0002796541,0.01115991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002876706,"threshold_uncertainty_score":0.009623528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02671542293300561,"score_gpt":0.3124031054529366,"score_spread":0.285687682519931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}