{"id":"W2606239694","doi":"10.1101/lm.044602.116","title":"Mutation of neuron-specific chromatin remodeling subunit BAF53b: rescue of plasticity and memory by manipulating actin remodeling","year":2017,"lang":"en","type":"article","venue":"Learning & Memory","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Hewitt Foundation; U.S. National Library of Medicine; National Institute on Drug Abuse; National Institute of Mental Health; National Institutes of Health; National Science Foundation","keywords":"Cofilin; Dendritic spine; Long-term potentiation; Neuroscience; Chromatin remodeling; Biology; Synaptic plasticity; Synapse; Hippocampus; Cell biology; Neuroplasticity; Phosphorylation; Cytoskeleton; Actin cytoskeleton; Chromatin; Hippocampal formation; Genetics; Cell","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005893159,0.0002137042,0.0003282001,0.00005894079,0.000394454,0.00005293426,0.0002663396,0.0001670895,0.00001654832],"category_scores_gemma":[0.0006914504,0.0002317626,0.00009187486,0.00004328897,0.0001478273,0.00002216492,0.0001859226,0.0002995719,0.000001608758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002074335,"about_ca_system_score_gemma":0.00005227804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000275564,"about_ca_topic_score_gemma":0.00002712062,"domain_scores_codex":[0.9983248,0.0001344401,0.0005231553,0.0004529474,0.0003091876,0.0002554542],"domain_scores_gemma":[0.9986021,0.00006339372,0.000585816,0.0004668259,0.0002073361,0.00007455237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001072801,0.00001773424,0.0005877624,0.0001372138,0.00002015613,0.000001581242,0.0002847701,0.1097785,0.8675418,0.000004550305,0.00009088909,0.02142774],"study_design_scores_gemma":[0.00144183,0.0002970106,0.003668452,0.0004299622,0.00005672677,0.0000431874,0.0007890431,0.2978505,0.6945689,0.00006368975,0.0003603857,0.0004303353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857342,0.0008332928,0.01226569,0.00006893852,0.0001264197,0.0001364273,0.000008719026,0.00002682508,0.0007994849],"genre_scores_gemma":[0.9939191,0.0002654578,0.005106539,0.00002029146,0.0001706546,0.000004523791,0.00005801701,0.00005133108,0.0004040895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.188072,"threshold_uncertainty_score":0.9451003,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01976076159402023,"score_gpt":0.2653226559475567,"score_spread":0.2455618943535365,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}