{"id":"W2606345593","doi":"10.1371/journal.ppat.1006229","title":"Elucidating the structure of an infectious protein","year":2017,"lang":"en","type":"review","venue":"PLoS Pathogens","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Alberta Prion Research Institute","keywords":"Computational biology; Protein structure; Virology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000136577,0.0002875703,0.0005789704,0.00003681676,0.000224247,0.00005388938,0.0006160683,0.0003257136,0.00003967818],"category_scores_gemma":[0.0003263169,0.0001883178,0.0003653591,0.00005062904,0.00007562462,0.000003615234,0.0002368992,0.0002053305,0.000004380384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001114766,"about_ca_system_score_gemma":0.0002245475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000744813,"about_ca_topic_score_gemma":0.00001294312,"domain_scores_codex":[0.9986995,0.0002200247,0.00033275,0.0003854443,0.0001498075,0.0002124395],"domain_scores_gemma":[0.9980538,0.00001198465,0.0006069719,0.001174916,0.00007308357,0.00007925303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000404509,0.00003146491,0.000005038739,0.002921935,0.0001650872,0.000004630136,0.000009963696,9.928804e-7,0.05506295,0.0000166952,0.00001442966,0.9417627],"study_design_scores_gemma":[0.0001282593,0.0001992401,0.000005852469,0.002788467,0.0005823094,0.00003430398,0.000008351453,0.000005699368,0.01856538,0.0000986964,0.9771864,0.0003970513],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006379615,0.9918659,0.00002721393,0.000003539324,0.00006438154,0.001004089,0.0005201768,0.00001179861,0.0001232973],"genre_scores_gemma":[0.007607462,0.9909865,0.0002477841,0.00001555767,0.0005206147,0.00006059583,0.0004395196,0.00005805536,0.00006391672],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.977172,"threshold_uncertainty_score":0.7679379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04396486587272962,"score_gpt":0.3300667737810184,"score_spread":0.2861019079082888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}