{"id":"W2606368128","doi":"10.3390/molecules22040635","title":"Na+i,K+i-Dependent and -Independent Signaling Triggered by Cardiotonic Steroids: Facts and Artifacts","year":2017,"lang":"en","type":"review","venue":"Molecules","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Symporter; Chemistry; Receptor; Cell biology; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Transmembrane protein; Biochemistry; Biophysics; Biology; Transporter","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002035926,0.0004569629,0.0008760239,0.00007795771,0.0001935361,0.0001539438,0.0002125867,0.0005398508,0.000007286981],"category_scores_gemma":[0.00002294036,0.0003984665,0.0002382911,0.00002781387,0.00009795538,0.000007523887,0.0001111973,0.0001871621,0.00000643607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002090447,"about_ca_system_score_gemma":0.0001090862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001587968,"about_ca_topic_score_gemma":0.00001079102,"domain_scores_codex":[0.9982595,0.00009413731,0.0004040836,0.0006933445,0.0002325497,0.0003163313],"domain_scores_gemma":[0.9989992,0.00001180119,0.0003222641,0.0004557873,0.00004713175,0.0001638147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003121043,0.00004350615,0.00002192257,0.003566115,0.0005543711,0.00004711586,0.00006323186,0.00000509195,0.01161181,0.00001223312,0.0002845198,0.9837589],"study_design_scores_gemma":[0.0005859282,0.0001703712,0.00004391204,0.001443296,0.0007194013,0.000103538,0.00003628051,0.00000692509,0.01001207,0.00002432768,0.9861107,0.0007432087],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01021445,0.9883086,0.0005063776,0.00001112098,0.0001537076,0.0005294469,0.0001171873,0.00001549512,0.0001435851],"genre_scores_gemma":[0.05345457,0.9443842,0.00004359502,0.00002039934,0.000130131,0.00003833448,0.0008845991,0.00006387854,0.0009803023],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9858262,"threshold_uncertainty_score":0.9998467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03823248747570823,"score_gpt":0.3009835027991609,"score_spread":0.2627510153234526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}