{"id":"W2606513582","doi":"10.1038/srep46574","title":"Biotin-transfer from a trifunctional crosslinker for identification of cell surface receptors of soluble protein ligands","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"National Research Council Canada","keywords":"Biotinylation; Streptavidin; Chemistry; Ligand (biochemistry); Biotin; Receptor; Peptide; Biochemistry; Combinatorial chemistry; Avidin; Linker","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002817325,0.0005861745,0.0002325305,0.0003693101,0.0002134723,0.0002388496,0.0004030191,0.0006965579,0.001215607],"category_scores_gemma":[0.0002035432,0.0002129523,0.0003493213,0.000156989,0.0002006932,0.0003877913,0.0003212249,0.0006460869,0.0008641811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003378174,"about_ca_system_score_gemma":0.0002027295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003820185,"about_ca_topic_score_gemma":0.0004806748,"domain_scores_codex":[0.999826,0.00003249063,0.00001143617,0.00004478313,0.00005422972,0.0000310814],"domain_scores_gemma":[0.9998819,0.00003519481,0.0000233903,0.00001603677,0.00002004741,0.00002347097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001432435,0.000008313251,0.00002803917,0.00003063834,0.000002809451,0.00003154168,0.000008908727,0.00003404836,0.9984723,0.0001034006,0.00002792112,0.001237812],"study_design_scores_gemma":[0.000005810663,0.00006839211,0.000248205,0.000003235321,0.000006135474,0.0003019276,0.000005221092,0.000779221,0.99582,0.00004214066,0.002714878,0.000004752608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.734293,0.005889255,0.2543617,0.0004862175,0.0001522447,0.0002743506,0.0004125235,0.0007918264,0.003338878],"genre_scores_gemma":[0.8318745,0.004210699,0.1558102,0.0002767422,0.00005956386,0.0002387474,0.0009372538,0.0001501186,0.006442072],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001215607,"threshold_uncertainty_score":0.004066586,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01301704302478401,"score_gpt":0.2527924301977998,"score_spread":0.2397753871730158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}