{"id":"W2606513582","doi":"10.1038/srep46574","title":"Biotin-transfer from a trifunctional crosslinker for identification of cell surface receptors of soluble protein ligands","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"National Research Council Canada","keywords":"Biotinylation; Streptavidin; Chemistry; Ligand (biochemistry); Biotin; Receptor; Peptide; Biochemistry; Combinatorial chemistry; Avidin; Linker","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000752055,0.0001024966,0.0001639025,0.00002950985,0.0004204735,0.00008043851,0.0001586477,0.0001844585,0.00001921336],"category_scores_gemma":[0.0001497008,0.00008718806,0.0001558235,0.00005348319,0.0004762152,0.00000851151,0.00006293823,0.00005281785,0.000001889264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000055564,"about_ca_system_score_gemma":0.0001090817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004569674,"about_ca_topic_score_gemma":0.00001621417,"domain_scores_codex":[0.998652,0.00001206888,0.000505581,0.0004840012,0.0001975302,0.0001487968],"domain_scores_gemma":[0.9984213,0.000007446422,0.0004269255,0.0007411793,0.000364159,0.00003897023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005847898,0.00009372126,0.00346465,0.0000461177,0.00005398117,8.115224e-7,0.00008397736,0.00002827399,0.9901431,0.000007327111,0.005889558,0.000130023],"study_design_scores_gemma":[0.0003037498,0.00006310107,0.002228868,0.00002745203,0.00002840891,0.000001740025,0.00005911609,0.00002772688,0.9849455,0.0003484367,0.01186887,0.0000970641],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992322,0.000438641,0.001562121,0.00006903524,0.004837278,0.000404062,0.00003053087,0.000005690496,0.0003306197],"genre_scores_gemma":[0.9800434,0.0000214099,0.0007409829,0.000002631217,0.00006967405,0.00001111335,0.0001940028,0.00001103426,0.01890581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01857519,"threshold_uncertainty_score":0.3555426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01301704302478401,"score_gpt":0.2527924301977998,"score_spread":0.2397753871730158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}