{"id":"W2606738177","doi":"10.1016/j.jnutbio.2017.02.010","title":"The metabolic fate of isotopically labeled trimethylamine-N-oxide (TMAO) in humans","year":2017,"lang":"en","type":"article","venue":"The Journal of Nutritional Biochemistry","topic":"Nutritional Studies and Diet","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Jianghan University","keywords":"Trimethylamine N-oxide; Trimethylamine; Urine; Chemistry; Monooxygenase; Feces; Flavin-containing monooxygenase; Metabolism; Endocrinology; Internal medicine; Biochemistry; Biology; Medicine; Microbiology; Cytochrome P450","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002288505,0.0002177283,0.0002285492,0.0002933407,0.0002622926,0.0004731545,0.0002076715,0.000557657,0.0008079346],"category_scores_gemma":[0.0003459486,0.0002718455,0.0001816185,0.0002239931,0.0003608867,0.0002979224,0.000138003,0.0004021646,0.0001762383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000365693,"about_ca_system_score_gemma":0.0003020303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003477051,"about_ca_topic_score_gemma":0.002029531,"domain_scores_codex":[0.9999188,0.00002567996,0.000003956516,0.00003084468,0.000008532923,0.00001214305],"domain_scores_gemma":[0.9998531,0.00003052265,0.00004945365,0.00002261588,0.00001917681,0.00002502013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.09391194,0.001067606,0.3409517,0.0004003048,0.000599843,0.003610948,0.001683616,0.0009154062,0.4710937,0.001561193,0.001012623,0.08319113],"study_design_scores_gemma":[0.000508496,0.009596605,0.8053755,0.00009296594,0.000876258,0.005915951,0.001767473,0.003734793,0.1629406,0.001500932,0.007611642,0.00007867623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972844,0.001748939,0.0002596843,0.00004375408,0.000008621837,0.000005480937,0.000110355,0.00000533916,0.0005332895],"genre_scores_gemma":[0.9981383,0.0006986455,0.0002347358,0.00004510866,0.000006912618,0.000007730153,0.0001407882,0.000005825706,0.0007218524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003477051,"threshold_uncertainty_score":0.006913602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01994256916645672,"score_gpt":0.3005353059419525,"score_spread":0.2805927367754958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}