{"id":"W2606765263","doi":"10.3390/molecules22040655","title":"Protein Stability and Unfolding Following Glycine Radical Formation","year":2017,"lang":"en","type":"article","venue":"Molecules","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Deutsche Forschungsgemeinschaft","keywords":"Chemistry; Tryptophan; Protein folding; Crystallography; Biophysics; Stereochemistry; Amino acid; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001235982,0.00009538247,0.00009104204,0.00001316975,0.0002667471,0.00007898996,0.0001431471,0.00009391062,0.000003140281],"category_scores_gemma":[0.0001915924,0.00008549128,0.00005008387,0.0000109799,0.00008049405,0.00001139726,0.0001476218,0.00005547994,0.000001013764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008504592,"about_ca_system_score_gemma":0.0000183741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001847845,"about_ca_topic_score_gemma":0.00003018518,"domain_scores_codex":[0.9994494,0.00002300906,0.0001105943,0.0001925269,0.00008309706,0.0001414218],"domain_scores_gemma":[0.9994842,0.000002618056,0.00006986602,0.0003704292,0.00001931136,0.00005355828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003336488,0.000007270585,0.00142814,0.00002191497,0.00001476342,0.000005455253,0.00002317097,0.000001380293,0.9933736,0.0006109616,0.00002260614,0.004457325],"study_design_scores_gemma":[0.0006102837,0.0001137998,0.00469397,0.00002579883,0.00001426418,0.00001376369,0.00002738136,0.0006143638,0.9894705,0.001552468,0.002687097,0.0001762477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9813699,0.0003433614,0.01678491,0.000225982,0.00005081515,0.0002040815,0.000005495898,0.00001064397,0.001004884],"genre_scores_gemma":[0.9964252,0.00001187542,0.003328391,0.00006250807,0.00007138803,0.00001713938,0.00003060316,0.000009308897,0.00004357833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01505538,"threshold_uncertainty_score":0.3486233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0096755394732968,"score_gpt":0.2479313551792176,"score_spread":0.2382558157059208,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}