{"id":"W2606922555","doi":"10.1172/jci.insight.92943","title":"T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response","year":2017,"lang":"en","type":"article","venue":"JCI Insight","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":184,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Human immunodeficiency virus (HIV); Virology; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002345507,0.0001453965,0.0001580795,0.00007162322,0.001909044,0.0001210657,0.0001930459,0.0002132986,0.0007529455],"category_scores_gemma":[0.000113634,0.0001032576,0.00006511458,0.00003050988,0.0002198943,0.0002563504,0.0001158717,0.0004473637,0.001123964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003802956,"about_ca_system_score_gemma":0.00001680746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001542985,"about_ca_topic_score_gemma":0.00003109075,"domain_scores_codex":[0.9990898,0.000287528,0.0001895895,0.0002137873,0.0000247094,0.0001946307],"domain_scores_gemma":[0.9990662,0.0001210642,0.0002281318,0.0005099518,0.0000575926,0.00001701165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002945717,0.00008677358,0.0003474858,0.000002700963,0.00005241935,0.00000150639,0.0004402084,1.530646e-7,0.9008008,0.0001634434,0.09722773,0.0005822403],"study_design_scores_gemma":[0.0007798538,0.0001689077,0.01382196,0.00001387108,0.00002198662,0.00001762077,0.0001602816,0.000001423025,0.3461735,0.00002465011,0.6387082,0.0001076857],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833347,0.0004343964,0.00001884965,0.001670963,0.003553355,0.0001728518,0.000009438564,0.00004945334,0.01075595],"genre_scores_gemma":[0.922623,0.0000525937,0.000001286258,0.0003457928,0.00004652907,0.00002229479,0.00003053418,0.00001275433,0.07686521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5546272,"threshold_uncertainty_score":0.9996538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01559324682918405,"score_gpt":0.2551219731310465,"score_spread":0.2395287263018624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}