{"id":"W2606926145","doi":"10.2174/1570159x15666170413115754","title":"Aripiprazole, A Drug that Displays Partial Agonism and Functional Selectivity","year":2017,"lang":"en","type":"article","venue":"Current Neuropharmacology","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"","keywords":"Aripiprazole; Partial agonist; Schizophrenia (object-oriented programming); Medicine; Antipsychotic; Atypical antipsychotic; Extrapyramidal symptoms; Pharmacology; Bipolar disorder; Cognition; Psychiatry; Internal medicine; Receptor; Antagonist","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000412484,0.0002709985,0.0007447337,0.002264603,0.0001324767,0.0005123734,0.0004267189,0.0004795472,0.00604207],"category_scores_gemma":[0.001166821,0.0001326104,0.0008034731,0.002338717,0.0003031306,0.0006057647,0.0002157757,0.000309807,0.0009765597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000575693,"about_ca_system_score_gemma":0.000990741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001230011,"about_ca_topic_score_gemma":0.003922758,"domain_scores_codex":[0.9996467,0.00005469895,0.0001182511,0.00006018136,0.0001053386,0.00001494237],"domain_scores_gemma":[0.9991956,0.0002900448,0.000398515,0.00001379466,0.00008132509,0.00002058078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001095392,0.0001117539,0.004366908,0.156301,0.001291195,0.00306867,0.0001098419,0.0004355154,0.02886811,0.003911019,0.02976955,0.770671],"study_design_scores_gemma":[0.001155408,0.001453308,0.03077351,0.0185474,0.00433024,0.02263738,0.0001980139,0.0006650342,0.01588621,0.002142105,0.902103,0.0001083807],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01331862,0.9657235,0.001457814,0.001551584,0.0002569668,0.0001638778,0.003496029,0.0001051812,0.0139266],"genre_scores_gemma":[0.1233176,0.8625447,0.005166625,0.001721288,0.0004156533,0.0002062397,0.002694439,0.00002483353,0.003908522],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00604207,"threshold_uncertainty_score":0.02021271,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07237708895088969,"score_gpt":0.3694698691423211,"score_spread":0.2970927801914314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}