{"id":"W2606982215","doi":"10.7759/cureus.1185","title":"Improving Therapeutic Ratios with the Oncotype DX® Ductal Carcinoma In Situ (DCIS) Score","year":2017,"lang":"en","type":"article","venue":"Cureus","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Health Sciences Centre; University of Toronto","funders":"","keywords":"Medicine; Ductal carcinoma; Breast cancer; Oncology; Internal medicine; Adjuvant radiotherapy; Radiation therapy; Cancer; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001801443,0.0004418005,0.0006341735,0.002080968,0.000290292,0.000929312,0.0003506189,0.000432321,0.003032658],"category_scores_gemma":[0.005431197,0.00008582541,0.0004141043,0.001291308,0.0002763541,0.0006297249,0.0007600822,0.0008834637,0.0009140975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006788432,"about_ca_system_score_gemma":0.0003392787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006801954,"about_ca_topic_score_gemma":0.0007711235,"domain_scores_codex":[0.9986398,0.0006143905,0.0001311691,0.0001276847,0.0004096041,0.00007729483],"domain_scores_gemma":[0.9989756,0.0003911772,0.0002299453,0.00008789734,0.000202449,0.0001129426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001230825,0.0003409694,0.1554814,0.000301118,0.0001601954,0.001108288,0.0002217848,0.002295668,0.008319117,0.003255518,0.01012275,0.8171625],"study_design_scores_gemma":[0.0005349565,0.008177774,0.6489903,0.0007602287,0.001384402,0.03222912,0.001328675,0.02634208,0.03780168,0.03047588,0.2117455,0.0002294305],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7609571,0.07287613,0.04159245,0.01523836,0.001246009,0.001020762,0.001682387,0.0007678934,0.1046188],"genre_scores_gemma":[0.9619645,0.009631027,0.02287061,0.0009307123,0.0004644998,0.0002710843,0.0007880213,0.00009707211,0.002982398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003032658,"threshold_uncertainty_score":0.01014525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01725221267447187,"score_gpt":0.2575414015733882,"score_spread":0.2402891888989163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}