{"id":"W2606982215","doi":"10.7759/cureus.1185","title":"Improving Therapeutic Ratios with the Oncotype DX® Ductal Carcinoma In Situ (DCIS) Score","year":2017,"lang":"en","type":"article","venue":"Cureus","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Health Sciences Centre; University of Toronto","funders":"","keywords":"Medicine; Ductal carcinoma; Breast cancer; Oncology; Internal medicine; Adjuvant radiotherapy; Radiation therapy; Cancer; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005353578,0.000125021,0.00009754081,0.000007902253,0.0002510014,0.00004514382,0.0002477294,0.00005251849,0.000005693762],"category_scores_gemma":[0.00001805627,0.00007607814,0.00003227322,0.000018679,0.0001364513,0.000006397016,0.0001191998,0.00006447695,0.000005123602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003177629,"about_ca_system_score_gemma":0.00007359125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004177457,"about_ca_topic_score_gemma":0.005587093,"domain_scores_codex":[0.9994368,0.00002003354,0.00006888284,0.0002278925,0.00007499938,0.0001714103],"domain_scores_gemma":[0.9993004,0.000007113367,0.00007836592,0.0005518792,0.00003867869,0.00002354165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004423961,0.0001466531,0.6700722,0.00002350095,0.0002706937,0.00005828908,0.0008132632,0.0000197172,0.3120587,0.0002502273,0.0008168189,0.01502749],"study_design_scores_gemma":[0.001203397,0.000278923,0.9302433,0.00001389517,0.00005822477,0.00003705499,0.0003300018,0.00001548102,0.06552164,0.00004294683,0.002052112,0.0002030426],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934918,0.002849364,0.00006068882,0.001179789,0.0001140558,0.0001714026,0.000005069552,0.000005989326,0.002121842],"genre_scores_gemma":[0.9992582,0.00005884228,0.00005218678,0.0001768271,0.0002317228,0.00004432198,0.00001193234,0.00001524663,0.0001507073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2601711,"threshold_uncertainty_score":0.3117729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01725221267447187,"score_gpt":0.2575414015733882,"score_spread":0.2402891888989163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}