{"id":"W2607015237","doi":"10.1213/xaa.0000000000000520","title":"Anesthetic Management of Mitochondrial Encephalopathy With Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome) in a High-Risk Pregnancy","year":2017,"lang":"en","type":"article","venue":"A & A Case Reports","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Medicine; Lactic acidosis; MELAS syndrome; Posterior reversible encephalopathy syndrome; Hypokalemia; Encephalopathy; Preeclampsia; Pregnancy; Coma (optics); Hyperkalemia; Intensive care unit; Anesthesia; Sepsis; Stroke (engine); Eclampsia; Intensive care medicine; Surgery; Internal medicine; Mitochondrial myopathy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001467395,0.000186987,0.0002724129,0.00006726798,0.0001436614,0.00003553414,0.00007342839,0.0001445816,0.00001871922],"category_scores_gemma":[0.00005754572,0.0001611719,0.0000617564,0.0000464386,0.0001441231,0.00001284568,0.0001181899,0.0001049566,0.000001689313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001008775,"about_ca_system_score_gemma":0.0000394494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004900965,"about_ca_topic_score_gemma":0.000544919,"domain_scores_codex":[0.9986758,0.00008691975,0.0003442259,0.0005331445,0.0001347189,0.0002251836],"domain_scores_gemma":[0.9985042,0.00001243853,0.0004692428,0.0008750251,0.00005069188,0.00008842138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00132784,0.0006182287,0.3273117,0.000520021,0.0004976398,0.5789915,0.0005025102,0.00004705964,0.05834512,0.0003478933,0.0001654865,0.03132502],"study_design_scores_gemma":[0.009552896,0.005952019,0.1309553,0.001463189,0.001044916,0.7756918,0.0008554807,0.000042895,0.06427806,0.0007469567,0.007837612,0.001578911],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970502,0.001072188,0.0005108715,0.00004025124,0.0004284359,0.0004229489,0.00001238153,0.000008790066,0.0004539669],"genre_scores_gemma":[0.9952145,0.0006167406,0.003267778,0.00001763559,0.00004266643,0.00009384855,0.0000168419,0.00002011621,0.0007098211],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1967003,"threshold_uncertainty_score":0.6572398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007532138924453575,"score_gpt":0.2306514995316278,"score_spread":0.2231193606071742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}