{"id":"W2607131923","doi":"10.1074/jbc.m116.765669","title":"New insights into the tetraspanin Tspan5 using novel monoclonal antibodies","year":2017,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National de la Santé et de la Recherche Médicale; Institut National Du Cancer; Association pour la Recherche sur le Cancer","keywords":"Tetraspanin; Endoplasmic reticulum; Notch signaling pathway; Monoclonal antibody; Cell biology; Biology; Antibody; ADAM10; Notch proteins; Transfection; HEK 293 cells; Signal transduction; Cell culture; Cell; Metalloproteinase; Immunology; Matrix metalloproteinase; Biochemistry; Disintegrin; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004821975,0.0006338699,0.0002405016,0.0006949559,0.0001793936,0.000374388,0.0005047668,0.000665669,0.001355473],"category_scores_gemma":[0.0002227665,0.0002960672,0.0005389153,0.0002789983,0.0001855873,0.0005202884,0.0003675507,0.0009117211,0.0004678908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005602062,"about_ca_system_score_gemma":0.0001884345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005803616,"about_ca_topic_score_gemma":0.001047356,"domain_scores_codex":[0.9997142,0.00006082511,0.00002838986,0.00006447533,0.00008003625,0.00005208699],"domain_scores_gemma":[0.999874,0.00003195029,0.00001507969,0.00001469513,0.00004138297,0.00002286699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003411334,0.00003009765,0.0001501479,0.0001004419,0.00001850627,0.0000665761,0.00002047778,0.00007669501,0.9913278,0.0004828768,0.0001900973,0.007502173],"study_design_scores_gemma":[0.00007990585,0.0007296366,0.006513645,0.00008783787,0.0001961097,0.002190793,0.00006369277,0.005270878,0.9219854,0.001180731,0.06166975,0.0000315705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.788569,0.05399698,0.1404351,0.001955833,0.0005356255,0.0002162403,0.0008716409,0.0007994454,0.01262002],"genre_scores_gemma":[0.8049316,0.04070044,0.1401488,0.001650042,0.0004362857,0.0002966832,0.002001175,0.0001274151,0.009707614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001355473,"threshold_uncertainty_score":0.004534483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09208427583306647,"score_gpt":0.3644191988414627,"score_spread":0.2723349230083962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}