{"id":"W2607733491","doi":"10.1007/7081_2017_204","title":"Aminolactam, N-Aminoimidazolone, and N-Aminoimdazolidinone Peptide Mimics","year":2017,"lang":"en","type":"book-chapter","venue":"Topics in heterocyclic chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Dihedral angle; Peptide; Residue (chemistry); Side chain; Chemistry; Stereochemistry; Amino acid residue; Amino acid; Ring (chemistry); Lactam; Peptide sequence; Biochemistry; Molecule; Organic chemistry; Hydrogen bond","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009631242,0.0005641353,0.0006541925,0.00004741989,0.0001172287,0.00008770407,0.000542224,0.0010848,0.0001676437],"category_scores_gemma":[0.0001144421,0.0005966976,0.0002980372,0.00001022452,0.0002938253,0.000005643547,0.0004938058,0.0005195565,0.0000143194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006984297,"about_ca_system_score_gemma":0.00003719332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002543139,"about_ca_topic_score_gemma":0.00005876417,"domain_scores_codex":[0.9978933,0.000009380997,0.0005187065,0.0009449454,0.0002300131,0.0004036774],"domain_scores_gemma":[0.998199,0.00002808284,0.000361267,0.001177957,0.00005045657,0.0001831691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001169781,0.000124098,0.002654691,0.0007601042,0.0004520203,0.0001480723,0.00005421944,0.000006043585,0.9649497,0.000352625,0.002339886,0.0280416],"study_design_scores_gemma":[0.0009362597,0.0000487071,0.0009456395,0.0004094041,0.0002159774,0.000111646,0.00001340095,0.00004393055,0.4499685,0.002047579,0.5437664,0.001492569],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.5618788,0.00315176,0.000009883362,0.0002283531,0.0001094969,0.0001836896,0.00009658333,0.00002630072,0.4343151],"genre_scores_gemma":[0.4489683,0.004649441,0.0001482507,0.0001305452,0.001346693,0.00002383113,0.0004410165,0.000104281,0.5441877],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5414265,"threshold_uncertainty_score":0.9996485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01546248399197554,"score_gpt":0.2417855765158958,"score_spread":0.2263230925239202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}