{"id":"W2607739553","doi":"10.1016/j.cellsig.2017.04.017","title":"IRE1α links Nck1 deficiency to attenuated PTP1B expression in HepG2 cells","year":2017,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Cell biology; Biology; Genetics; Molecular biology; Cancer research; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003250081,0.0002201773,0.0001931609,0.00006587803,0.0002855901,0.0001202543,0.0007162593,0.0002827684,0.00003443323],"category_scores_gemma":[0.0001857433,0.0002225045,0.00008315003,0.0000697534,0.00006647302,0.00001145164,0.0003845179,0.0002273717,0.00009215107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002147714,"about_ca_system_score_gemma":0.000058403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006208303,"about_ca_topic_score_gemma":0.00002029829,"domain_scores_codex":[0.9984745,0.00005191737,0.0002883067,0.0005742849,0.0001864727,0.0004244668],"domain_scores_gemma":[0.9987695,0.00001322815,0.0001566597,0.0008387403,0.00007186417,0.0001500735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000501551,0.00005539961,0.001129496,0.00002214025,0.000004696995,0.00003043786,0.00003659527,0.0007584172,0.9962575,0.00004126391,0.0004397981,0.001174138],"study_design_scores_gemma":[0.0004067965,0.0001280143,0.0005469851,0.000121944,0.000007698191,0.000001695725,0.00002216767,0.0002512391,0.9942611,0.00007530975,0.003884745,0.0002922575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9723496,0.005793868,0.02052211,0.0001515725,0.0002623606,0.000417588,0.00002250362,0.00002358696,0.0004567873],"genre_scores_gemma":[0.9951614,0.00008638047,0.003880956,0.0001814104,0.0002010397,0.00003959779,0.0001006341,0.00003910922,0.0003094585],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02281179,"threshold_uncertainty_score":0.9073472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01544640627904202,"score_gpt":0.252858394035452,"score_spread":0.2374119877564099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}