{"id":"W2607754295","doi":"10.1200/jco.2016.70.5319","title":"Comparative Analysis of Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer According to 2007 and 2013 American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Clinical Oncology; Breast cancer; Internal medicine; Human Epidermal Growth Factor Receptor 2; Oncology; Guideline; Cancer; Immunohistochemistry; Metastatic breast cancer; Biomarker; Gynecology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","sts"],"consensus_categories":[],"category_scores_codex":[0.01225064,0.0002256096,0.006027276,0.0004982785,0.0001142838,0.00000747408,0.0005721374,0.0003302195,0.0003372873],"category_scores_gemma":[0.01396277,0.0001777017,0.0008989936,0.0009858003,0.003056703,0.0001592349,0.0003638267,0.001719551,0.000001631878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004125198,"about_ca_system_score_gemma":0.003112516,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006857608,"about_ca_topic_score_gemma":0.002528097,"domain_scores_codex":[0.98946,0.001758276,0.007364747,0.0004354508,0.0005576317,0.0004239193],"domain_scores_gemma":[0.9753225,0.009498002,0.01122219,0.0004758147,0.002860925,0.0006205178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001635068,0.001482429,0.8161253,0.00004139368,0.001386951,0.00003343248,0.0002603401,0.00004596174,0.001391816,0.000009273993,0.02169193,0.1558961],"study_design_scores_gemma":[0.003561039,0.0112412,0.9749068,0.0002321986,0.0008032638,0.00002999326,0.002574587,0.001027761,0.0001154147,0.0000206733,0.005349479,0.0001375776],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9513592,0.00008103615,0.0001509628,0.04658877,0.000420865,0.0003542824,0.0004800077,0.000005135732,0.0005597288],"genre_scores_gemma":[0.9447803,0.001644662,0.0513831,0.001398463,0.0007155731,0.00001240327,0.00000829281,0.0000168593,0.00004031831],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1587815,"threshold_uncertainty_score":0.9997558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4768977260122448,"score_gpt":0.6404764171538218,"score_spread":0.1635786911415769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}