{"id":"W2607859402","doi":"10.1093/sleepj/zsx050.674","title":"0675 A RANDOMIZED, PLACEBO-CONTROLLED, PHASE 3 STUDY OF THE SAFETY AND EFFICACY OF JZP-110 FOR THE TREATMENT OF EXCESSIVE SLEEPINESS IN PATIENTS WITH NARCOLEPSY","year":2017,"lang":"en","type":"article","venue":"SLEEP","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Narcolepsy; Epworth Sleepiness Scale; Medicine; Placebo; Clinical endpoint; Cataplexy; Modafinil; Adverse effect; Population; Randomized controlled trial; Sleep disorder; Wakefulness; Somnolence; Excessive daytime sleepiness; Internal medicine; Physical therapy; Psychology; Polysomnography; Psychiatry; Insomnia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00116162,0.001450054,0.002173351,0.0005807639,0.00055842,0.0009000303,0.000888703,0.001744812,0.01168115],"category_scores_gemma":[0.001117936,0.0006840723,0.001532416,0.0003888166,0.001025508,0.0008053826,0.0003435834,0.00251074,0.001745091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005347905,"about_ca_system_score_gemma":0.001703014,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001313397,"about_ca_topic_score_gemma":0.004845527,"domain_scores_codex":[0.9995565,0.0002040052,0.00003475857,0.00007023561,0.00005296557,0.00008138729],"domain_scores_gemma":[0.9994122,0.0001753815,0.00009261261,0.00003444172,0.00005622287,0.0002292232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.941458,0.01939267,0.0006964041,0.001274566,0.001086042,0.000113844,0.0001112076,0.0003625531,0.008195018,0.0003427771,0.003089036,0.02387784],"study_design_scores_gemma":[0.9083446,0.08881485,0.001306691,0.00002262925,0.0001300915,0.00002597179,0.00001574626,0.00015176,0.0002750376,0.00005801397,0.0008415278,0.00001319162],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9601866,0.004666893,0.001080015,0.0006779076,0.000600833,0.01960296,0.004069784,0.0004250401,0.00868992],"genre_scores_gemma":[0.9661798,0.003091179,0.003439093,0.002466319,0.0003699548,0.01386171,0.003364412,0.00005032164,0.007177231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01168115,"threshold_uncertainty_score":0.03907728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02404656389669357,"score_gpt":0.3197162130426724,"score_spread":0.2956696491459788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}