{"id":"W2607944311","doi":"10.1038/leu.2017.122","title":"Efficacy and safety of carfilzomib regimens in multiple myeloma patients relapsing after autologous stem cell transplant: ASPIRE and ENDEAVOR outcomes","year":2017,"lang":"en","type":"article","venue":"Leukemia","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Leukemia & Lymphoma Society of Canada","funders":"Onyx Pharmaceuticals; Amgen","keywords":"Carfilzomib; Lenalidomide; Medicine; Autologous stem-cell transplantation; Multiple myeloma; Oncology; Internal medicine; Dexamethasone; Bortezomib; Hazard ratio; Salvage therapy; Transplantation; Chemotherapy; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001272454,0.0002086418,0.0004833201,0.0001193785,0.0001785719,0.00003036563,0.00009931833,0.0001469573,0.00001163391],"category_scores_gemma":[0.00008370513,0.0001615831,0.00005739253,0.00003974064,0.0001971786,0.0001297658,0.00009341798,0.0002248607,0.000006017934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001956537,"about_ca_system_score_gemma":0.00009157771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006170988,"about_ca_topic_score_gemma":0.0002105909,"domain_scores_codex":[0.9986297,0.00005681199,0.0003197378,0.0003544079,0.0002504322,0.000388895],"domain_scores_gemma":[0.9989412,0.0001887691,0.0001353124,0.0004761157,0.00004755642,0.0002110882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002415142,0.0001378972,0.9602523,0.0002532373,0.00007255932,0.000470115,0.001272156,9.606562e-7,0.0004187232,0.000008236118,0.00001173215,0.03468694],"study_design_scores_gemma":[0.0201639,0.0003048493,0.9767059,0.0003085934,0.00006679549,0.00001753661,0.00006893268,0.0002264616,0.001888203,0.000006874659,0.0001118179,0.0001301136],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972523,0.0004081299,0.000004782154,0.000117233,0.00005438545,0.000710175,0.00006972415,0.00002120068,0.001362085],"genre_scores_gemma":[0.9985772,0.0001597873,0.0003115126,0.0000362086,0.00001407169,0.0000291983,0.00002760905,0.0000237996,0.0008205844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03455683,"threshold_uncertainty_score":0.6589169,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01937783906273831,"score_gpt":0.2684230750100851,"score_spread":0.2490452359473468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}