{"id":"W2608572471","doi":"10.1093/neuonc/nox036.057","title":"OS08.7 The somatic landscape of Schwannoma","year":2017,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Neurofibromatosis and Schwannoma Cases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Schwannoma; Biology; Fusion gene; Cancer research; Somatic cell; Schwann cell; Gene; Exome; MAPK/ERK pathway; Exome sequencing; Genetics; Pathology; Mutation; Cell biology; Medicine; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002497199,0.0002090527,0.0001676439,0.0007171353,0.0002632439,0.0008744848,0.0001631184,0.0003863053,0.0138978],"category_scores_gemma":[0.0003965457,0.00009219789,0.000118812,0.0005451927,0.0002597893,0.0002345583,0.0003056539,0.000234145,0.005326578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003906016,"about_ca_system_score_gemma":0.000378004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005523062,"about_ca_topic_score_gemma":0.001226944,"domain_scores_codex":[0.9998593,0.00001156454,0.00001286329,0.00002482365,0.00005950922,0.00003188792],"domain_scores_gemma":[0.9998633,0.00002314737,0.00002655768,0.00001384855,0.00002987191,0.00004321324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.002683323,0.0002545723,0.10595,0.0005966885,0.00007775331,0.02264844,0.0003820679,0.001062046,0.2016753,0.01347459,0.06195696,0.5892381],"study_design_scores_gemma":[0.0003622096,0.001103523,0.1533539,0.000320739,0.0001613321,0.1233591,0.0006264512,0.002726949,0.07028257,0.01087967,0.6367738,0.00004967714],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7631811,0.009292062,0.004822066,0.002797697,0.0004858734,0.0001406406,0.008500043,0.001569975,0.2092104],"genre_scores_gemma":[0.9255047,0.003856116,0.005318105,0.0008839964,0.0002104664,0.00006820729,0.01140231,0.0003371025,0.05241895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0138978,"threshold_uncertainty_score":0.04649282,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03415723211864221,"score_gpt":0.3145988090398404,"score_spread":0.2804415769211983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}