{"id":"W2608624392","doi":"10.1093/eurheartj/ehx196","title":"Biased ligand of the angiotensin II type 1 receptor in patients with acute heart failure: a randomized, double-blind, placebo-controlled, phase IIB, dose ranging trial (BLAST-AHF)","year":2017,"lang":"en","type":"article","venue":"European Heart Journal","topic":"Heart Failure Treatment and Management","field":"Medicine","cited_by":145,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institutes of Health","keywords":"Medicine; Heart failure; Placebo; Dose-ranging study; Angiotensin II; Internal medicine; Cardiology; Randomized controlled trial; Double blind; Receptor; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002654902,0.0003388101,0.001271785,0.0002967743,0.0007051147,0.000179984,0.0002459172,0.0000646032,0.0001480978],"category_scores_gemma":[0.0004293978,0.0001867297,0.0005366597,0.0002084367,0.0002123038,0.0002620007,0.000160305,0.0005526784,0.00006802638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007990193,"about_ca_system_score_gemma":0.0001955712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002625654,"about_ca_topic_score_gemma":0.00002194119,"domain_scores_codex":[0.9970555,0.0007064232,0.0007868426,0.0003146324,0.0006586835,0.0004779568],"domain_scores_gemma":[0.9980656,0.0001491204,0.0005458999,0.0007145759,0.0002586411,0.0002661886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9690848,0.001090421,0.003499052,0.00001119505,0.0008102178,0.0001115187,0.0003631422,0.00001007341,0.0006783633,0.00000731428,0.02394712,0.000386795],"study_design_scores_gemma":[0.9685351,0.002509589,0.003166788,0.0004774627,0.0007737853,0.00008865879,0.00003360512,0.0000389155,0.0005086659,0.000001879017,0.02367781,0.0001877317],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804927,0.00007319511,0.00002203389,0.01329924,0.0009111488,0.004575296,0.00000582338,0.00002767358,0.000592952],"genre_scores_gemma":[0.9952672,0.00002039263,0.001966177,0.0003684525,0.0006996858,0.00002337397,0.00001319752,0.00006694462,0.001574577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01477457,"threshold_uncertainty_score":0.7614616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0356407885271743,"score_gpt":0.3071360147483303,"score_spread":0.271495226221156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}