{"id":"W2608670027","doi":"10.4049/jimmunol.1602131","title":"Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses","year":2017,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Wellcome Trust","keywords":"TLR7; TLR2; Immune system; Dual (grammatical number); Ligand (biochemistry); Enhanced Data Rates for GSM Evolution; Cell biology; Immunology; Biology; Chemistry; Receptor; Toll-like receptor; Innate immune system; Genetics; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001835229,0.00022048,0.0004878517,0.0002245554,0.001121037,0.00008337116,0.0004558694,0.0003086185,0.00002878292],"category_scores_gemma":[0.0008843098,0.0001456459,0.00008017744,0.00005095145,0.000997438,0.0003733203,0.0003521712,0.0007832205,0.00004764503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002863582,"about_ca_system_score_gemma":0.0001328597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000137107,"about_ca_topic_score_gemma":0.000004704342,"domain_scores_codex":[0.997907,0.0008290994,0.0006927418,0.000140816,0.00005740284,0.0003729087],"domain_scores_gemma":[0.9974164,0.0007290128,0.001207301,0.0004349758,0.0001884522,0.00002388509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003263697,0.0000493129,0.000592329,0.00001119749,0.000314857,0.00003681778,0.001990957,5.906282e-7,0.9857138,0.0001324656,0.0002058569,0.00768807],"study_design_scores_gemma":[0.003480549,0.001154814,0.2225105,0.0001062202,0.0001715245,0.003897044,0.002004687,0.000002591624,0.7612867,0.0001901156,0.00499211,0.0002031205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9563028,0.03923407,0.00001088866,0.003186713,0.0008856299,0.0001332408,0.000004380544,0.00001517165,0.000227071],"genre_scores_gemma":[0.9930555,0.005694039,0.00003628622,0.00007624443,0.00007700983,0.000002340317,0.000005696257,0.00001750874,0.001035334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2244271,"threshold_uncertainty_score":0.862222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01403837669159117,"score_gpt":0.24359632017047,"score_spread":0.2295579434788788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}