{"id":"W2608671054","doi":"10.1161/atvb.32.suppl_1.a544","title":"Abstract 544: Extracellular Heat Shock Protein 27 Inhibits Foam Cell Formation by Targeting Scavenger Receptor-A in the Vessel Wall","year":2012,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Scavenger receptor; Foam cell; Heat shock protein; Chemistry; Molecular biology; Hsp27; Extracellular; CD36; Flow cytometry; Downregulation and upregulation; Transfection; Western blot; Receptor; Hsp70; Biology; Cholesterol; Biochemistry; Lipoprotein; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000141902,0.0005760072,0.000348334,0.0002391671,0.0001327509,0.0001976074,0.0002126522,0.0003246168,0.004865235],"category_scores_gemma":[0.0001129461,0.0001397288,0.0004044217,0.0001145196,0.0003131295,0.000156318,0.0002031202,0.0007585782,0.001201328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001969188,"about_ca_system_score_gemma":0.0002218608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003714988,"about_ca_topic_score_gemma":0.0003282208,"domain_scores_codex":[0.9998844,0.00002205499,0.000009866111,0.00001859664,0.00003223413,0.00003287446],"domain_scores_gemma":[0.9998817,0.00001768711,0.00003166724,0.00001405622,0.00001893211,0.00003586994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002792455,0.0000574702,0.00005764046,0.00005526053,0.000007499569,0.00003979269,0.000005366938,0.00003130216,0.9982887,0.0000398868,0.0001088903,0.001029053],"study_design_scores_gemma":[0.00007894697,0.001064307,0.002672437,0.000009205261,0.00002792156,0.0001701656,0.00001269185,0.0004149888,0.9939058,0.00004301254,0.001597614,0.000002793654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908521,0.002223351,0.003352028,0.0003625424,0.00008886802,0.00005486761,0.0007298538,0.0002341722,0.00210243],"genre_scores_gemma":[0.9833107,0.001593,0.002920896,0.0001502947,0.00007637579,0.0001041764,0.001641418,0.00006476862,0.01013838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004865235,"threshold_uncertainty_score":0.01627582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02504425854700915,"score_gpt":0.2705321418952876,"score_spread":0.2454878833482785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}