{"id":"W2608857402","doi":"10.1111/hae.13227","title":"Safety and effectiveness of room temperature stable recombinant factor <scp>VII</scp>a in patients with haemophilia A or B and inhibitors: Results of a multinational, prospective, observational study","year":2017,"lang":"en","type":"article","venue":"Haemophilia","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Novo Nordisk; Ministère de l'Économie, de la Science et de l'Innovation - Québec","keywords":"Medicine; Haemophilia; Haemophilia A; Adverse effect; Observational study; Seroconversion; Immunogenicity; Recombinant factor VIIa; Surgery; Internal medicine; Antibody; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003286963,0.0004723569,0.0009941217,0.0004634415,0.0003712534,0.0008758895,0.0003860263,0.000899,0.001962645],"category_scores_gemma":[0.004301822,0.0004087001,0.001824688,0.0007832492,0.0006278412,0.0009132439,0.0003461777,0.0007788189,0.0003532323],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004848616,"about_ca_system_score_gemma":0.0004070008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008318162,"about_ca_topic_score_gemma":0.0006321881,"domain_scores_codex":[0.9980261,0.0009065831,0.0002768415,0.0003777563,0.0002757439,0.0001368958],"domain_scores_gemma":[0.9936533,0.002015321,0.003086701,0.0003245441,0.0002948846,0.000625232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01662291,0.001016553,0.9752936,0.000202966,0.001338543,0.0001567051,0.0001878255,0.0001245315,0.0005701687,0.00002271238,0.0001766244,0.004286714],"study_design_scores_gemma":[0.002328935,0.01922325,0.9754111,0.00005759668,0.0009326887,0.0006040062,0.0002381892,0.0005118455,0.0001674056,0.00003835775,0.0004586922,0.00002805579],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987603,0.0007999307,0.00004848425,0.0000261761,0.000005060309,0.00003778003,0.000172623,0.000001465798,0.0001480897],"genre_scores_gemma":[0.9990224,0.0003106144,0.0001008882,0.00005827528,0.00002389296,0.00004269972,0.0003607183,0.000001409192,0.00007901921],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003286963,"threshold_uncertainty_score":0.01738328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03886121135024534,"score_gpt":0.3130083143306357,"score_spread":0.2741471029803904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}