{"id":"W2608878607","doi":"10.1016/j.breast.2017.04.007","title":"New agents for endocrine resistance in breast cancer","year":2017,"lang":"en","type":"review","venue":"The Breast","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Charles-Le Moyne; Centre intégré de santé et de services sociaux de Chaudière-Appalaches; Université de Sherbrooke","funders":"","keywords":"Endocrine system; Breast cancer; Medicine; Disease; Acquired resistance; Estrogen receptor; Oncology; Metastatic breast cancer; Internal medicine; Blockade; Estrogen; Cancer; Bioinformatics; Cancer research; Receptor; Hormone; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000364106,0.0005901409,0.0008278413,0.001787658,0.0002319245,0.0006931858,0.0005943542,0.0007495972,0.006808183],"category_scores_gemma":[0.0005482148,0.0001818065,0.0005507032,0.0010554,0.0002653155,0.000893449,0.0006010982,0.001907511,0.002888518],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003597022,"about_ca_system_score_gemma":0.0005172685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005372246,"about_ca_topic_score_gemma":0.001343864,"domain_scores_codex":[0.9998357,0.00003089775,0.00002253447,0.00002537477,0.00006842041,0.00001701815],"domain_scores_gemma":[0.9998232,0.00007890897,0.00002735497,0.000007406279,0.0000489743,0.00001418946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006729578,0.0001044173,0.000113588,0.01054064,0.00007050714,0.0001725718,0.00005182713,0.0002097204,0.002324975,0.003442627,0.02648784,0.956414],"study_design_scores_gemma":[0.00002288421,0.0001012188,0.0003867132,0.001854221,0.00006839095,0.001049986,0.00002537215,0.00006572116,0.0005783903,0.00110708,0.9947298,0.0000102405],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002487339,0.9967104,0.0002036532,0.0003088458,0.0003069882,0.00001269751,0.0000383851,0.00001469089,0.002155534],"genre_scores_gemma":[0.00140008,0.9960665,0.0003339936,0.0003507533,0.0001839175,0.00001613089,0.0000835878,0.000003253218,0.001561829],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006808183,"threshold_uncertainty_score":0.02277565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1116835301033755,"score_gpt":0.4349999707624004,"score_spread":0.3233164406590249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}