{"id":"W2608951168","doi":"10.1182/blood.v120.21.2560.2560","title":"A Highly Selective Anti-ROR1 Monoclonal Antibody Inhibits Human Acute Myeloid Leukemia CD34+ Cell Survival and Self-Renewal.","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; BC Cancer Agency","funders":"","keywords":"Biology; Myeloid leukemia; Leukemia; Cancer research; Stem cell; CD34; Acute leukemia; Stromal cell; Bone marrow; Population; Myeloid; Immunology; Molecular biology; Medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002039255,0.000360658,0.0002753471,0.0003004461,0.000143704,0.0001377136,0.0002647177,0.000268637,0.001889963],"category_scores_gemma":[0.0001120817,0.0001628376,0.0001923542,0.0001949419,0.0001238883,0.00009839545,0.0001700121,0.0004626237,0.0007353549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002314211,"about_ca_system_score_gemma":0.0001912414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004050194,"about_ca_topic_score_gemma":0.001078937,"domain_scores_codex":[0.9998038,0.00004226303,0.00001247019,0.00003013302,0.00005308226,0.000058267],"domain_scores_gemma":[0.9999253,0.00002030441,0.00001094165,0.00000962484,0.00001229583,0.00002158023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000841693,0.00006075713,0.0001203984,0.00002340134,0.000004256206,0.0000169012,0.000004965702,0.00003788164,0.9976546,0.00004924441,0.00009653051,0.001846847],"study_design_scores_gemma":[0.00007389719,0.001248382,0.005195094,0.000007777164,0.00002711379,0.0004093044,0.000008212834,0.001178671,0.9876917,0.00002791992,0.00412899,0.000002811169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876725,0.00407472,0.003641762,0.0001385765,0.00004301894,0.0001107401,0.0003699106,0.0001993568,0.003749457],"genre_scores_gemma":[0.9864146,0.0018172,0.005476034,0.00007959566,0.00002786731,0.0001159658,0.001555451,0.00002389597,0.004489285],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001889963,"threshold_uncertainty_score":0.006322563,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01692193652536604,"score_gpt":0.2999752665694249,"score_spread":0.2830533300440588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}