{"id":"W2609196580","doi":"10.1080/2162402x.2017.1321184","title":"Mapping the human T cell repertoire to recurrent driver mutations in MYD88 and EZH2 in lymphoma","year":2017,"lang":"en","type":"article","venue":"OncoImmunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Canada's Michael Smith Genome Sciences Centre; University of Victoria; Simon Fraser University; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Lymphoma; CD8; Human leukocyte antigen; Immunology; Cytotoxic T cell; Antigen; Immune system; T cell; Biology; Cancer research; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001194275,0.0001026758,0.00009635347,0.0003172903,0.0001831693,0.0002119626,0.0001208835,0.0002039313,0.001505679],"category_scores_gemma":[0.0002277791,0.0001018381,0.0001050737,0.0001831927,0.0001752792,0.00008891908,0.0001998947,0.0001903707,0.0002131496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001316441,"about_ca_system_score_gemma":0.0000498553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005368868,"about_ca_topic_score_gemma":0.0006447911,"domain_scores_codex":[0.9999013,0.00001944648,0.000009349529,0.00002747374,0.00001442122,0.00002811086],"domain_scores_gemma":[0.9999087,0.00003290048,0.000009167135,0.00001568344,0.000008783989,0.00002471414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008230452,0.00009013055,0.05799864,0.00002441842,0.00002712708,0.001910747,0.0004908065,0.0002471965,0.9298116,0.0001831292,0.0001338247,0.008259251],"study_design_scores_gemma":[0.0001492836,0.001949675,0.7030956,0.00002330632,0.0001625653,0.02882378,0.001334555,0.003846248,0.255319,0.0005177263,0.004756266,0.00002188975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994094,0.00003564724,0.0001595485,0.000007379685,0.000001307667,0.000004242633,0.00003350246,0.000003937314,0.0003450288],"genre_scores_gemma":[0.9995868,0.0000248117,0.00009226661,0.00001272146,0.000001482015,0.000004522828,0.00008216903,0.000003233207,0.0001921002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001505679,"threshold_uncertainty_score":0.00503695,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0506683785153188,"score_gpt":0.3452434549276915,"score_spread":0.2945750764123727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}