{"id":"W2609244474","doi":"10.3233/blc-170105","title":"CDK4/6 Inhibitors in Cancer Therapy: A Novel Treatement Strategy for Bladder Cancer","year":2017,"lang":"en","type":"review","venue":"Bladder Cancer","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Bladder cancer; Cancer; Oncology; Disease; Internal medicine; Targeted therapy; Chemotherapy; Cisplatin; Blockade","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0002923324,0.00170556,0.004284999,0.0005765781,0.0003239718,0.0001940695,0.0006473523,0.0009766499,0.002928508],"category_scores_gemma":[0.00003074778,0.001269827,0.001481368,0.0004748997,0.0002437978,0.0002711845,0.0001242509,0.0008547062,0.00004551894],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002442919,"about_ca_system_score_gemma":0.007093614,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01971462,"about_ca_topic_score_gemma":0.009835042,"domain_scores_codex":[0.9942186,0.00009924945,0.001561916,0.001851798,0.000791578,0.001476884],"domain_scores_gemma":[0.9965439,0.0001227016,0.001087193,0.001427926,0.0003298432,0.0004884101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003689923,0.000815859,0.0004885419,0.007134482,0.004363078,0.00004834301,0.0002786333,0.00002023631,0.00001380288,0.00002434426,0.01905883,0.9673849],"study_design_scores_gemma":[0.008878308,0.000542984,0.0003827549,0.02204101,0.004231605,0.00002268098,0.00005447205,0.00001691693,0.00008893179,0.0000277488,0.9625036,0.001209028],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007522836,0.9814702,0.00001915467,0.0006882133,0.002298541,0.008568387,0.003721035,0.0001235213,0.003035709],"genre_scores_gemma":[0.0002743261,0.9451845,0.00008186814,0.0007348441,0.003734041,0.03240686,0.0003316097,0.000465621,0.01678631],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9661759,"threshold_uncertainty_score":0.9995691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3195829308764018,"score_gpt":0.4846936988295876,"score_spread":0.1651107679531858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}