{"id":"W2609251157","doi":"10.1007/s00424-017-1981-3","title":"CK2 is a key regulator of SLC4A2-mediated Cl−/HCO3 − exchange in human airway epithelia","year":2017,"lang":"en","type":"article","venue":"Pflügers Archiv - European Journal of Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fondazione per la Ricerca sulla Fibrosi Cistica; Cystic Fibrosis Trust; Medical Research Council; Wellcome; Higher Committee for Education Development in Iraq; Wellcome Trust","keywords":"Cell biology; Epithelial polarity; Secretion; Chemistry; DIDS; Chloride channel; Respiratory epithelium; Apical membrane; Transfection; Calmodulin; Cystic fibrosis transmembrane conductance regulator; HEK 293 cells; Epithelium; Biology; Biochemistry; Cell; Receptor; Membrane; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001369176,0.0003304774,0.0003367404,0.0002432419,0.0002824514,0.0003884198,0.0001333718,0.0003111295,0.001210052],"category_scores_gemma":[0.000164869,0.0001562908,0.0002773254,0.000218589,0.0001405318,0.000166271,0.0002003794,0.0002528876,0.0004076131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003332359,"about_ca_system_score_gemma":0.000292344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001239257,"about_ca_topic_score_gemma":0.0011003,"domain_scores_codex":[0.9998308,0.00001829293,0.00001873125,0.00004618615,0.00005571023,0.00003022617],"domain_scores_gemma":[0.9999207,0.000006618485,0.00002944859,0.000005615353,0.00001897486,0.0000186165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002383062,0.00001388924,0.001920033,0.0001325021,0.00002383452,0.0002337337,0.0000250073,0.00007639771,0.9945116,0.00008916418,0.0002347423,0.002500874],"study_design_scores_gemma":[0.00007959753,0.0002871002,0.1336361,0.00003848461,0.0001539885,0.003559234,0.0001200007,0.00307578,0.8353469,0.0001954553,0.02347954,0.00002780834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9683837,0.02076171,0.0055008,0.0004817203,0.0001623012,0.00006670713,0.001712886,0.0002312593,0.002698998],"genre_scores_gemma":[0.9907608,0.002821158,0.001879802,0.0001020227,0.000038464,0.00003909029,0.001546316,0.00002258344,0.002789859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001239257,"threshold_uncertainty_score":0.004048049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01298520144407785,"score_gpt":0.2438423032686506,"score_spread":0.2308571018245728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}